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Gene-centric gene-gene interaction: A model-based kernel machine method
Allele matching kernel association study gene-clustered SNPs genomic similarity reproducing kernel Hilbert space quantitative traits
2012/11/23
Much of the natural variation for a complex trait can be explained by variation in DNA sequence levels. As part of sequence variation, gene-gene interaction has been ubiquitously observed in nature, w...
Reverse Engineering Gene Interaction Networks Using the Phi-Mixing Coefficient
Reverse Engineering Gene Interaction Networks Phi-Mixing Coefficient
2012/9/18
In this paper, we present a new algorithm for reverse-engineering gene interaction networks (GINs) from expression data, by viewing the expres-sion levels of various genes as coupled random variables....