搜索结果: 1-14 共查到“知识库 HEPCIDIN”相关记录14条 . 查询时间(0.068 秒)
研究放疗相关性贫血患者血清铁调素（Hepcidin，Hep）和促红细胞生成素（EPO）表达特征及其意义。方法 对接受放疗的92 例肿瘤患者和20 例对照组测定血红蛋白（Hb），并应用双抗夹心生物素- 亲和素- 酶联免疫吸附试验方法检测Hep 和EPO，并分析其相关关系和临床意义。
COPD合并呼吸衰竭患者血清HEPCIDIN表达及与预后评估关系
慢性双向性肺疾病 呼吸衰竭 HEPCIDIN
2020/12/23
探讨COPD合并呼吸衰竭患者血清铁调素表达及与预后评估。方法：本院COPD合并呼吸衰竭患者115例为病例组，我院门诊健康体检者52例作为对照组，测定各组CRP，WBC ，HEPCIDIN，FEV1％，FEV1 / FVC，DLCO％水平，同时测定不同程度的低氧血症COPD合并呼吸衰竭患者的HEPCIDIN水平。
The effects of fat loss after bariatric surgery on inflammation, serum hepcidin, and iron absorption: a prospective 6-mo iron stable isotope study
obesity iron deficiency iron absorption hepcidin inflammation stable isotopes
2018/12/14
Background: Iron deficiency is common in obese subjects. This may be due to an increase in serum hepcidin and a decrease in iron absorption from adiposity-related inflammation.
The effects of fat loss after bariatric surgery on inflammation, serum hepcidin, and iron absorption: a prospective 6-mo iron stable isotope study
obesity iron deficiency iron absorption hepcidin inflammation stable isotopes
2018/12/18
Background: Iron deficiency is common in obese subjects. This may be due to an increase in serum hepcidin and a decrease in iron absorption from adiposity-related inflammation.
Relationship Between Serum Hepcidin and Ferritin Levels in Patients With Thalassemia Major and Intermedia in Southern Iran
Hepcidin Hydroxyurea Ferritin Thalassemia Intermedia Thalassemia Major
2015/11/9
Background: Hepcidin is a key regulator of iron absorption in humans. It is mainly affected by hypoxia and iron stores.
A seven day running training period increases basal urinary hepcidin levels as compared to cycling
Iron deficiency Weight-bearing exercise Non-weight-bearing exercise Cytokines
2015/7/29
This investigation compared the effects of an extended period of weight-bearing (running) vs. non-weight-bearing (cycling) exercise on hepcidin production and its implications for iron status.Ten acti...
Do High Blood Hepcidin Concentrations Contribute to Low Ferritin Levels in Young Tennis Players at the End of Tournament Season?
Pro-inflammatory cytokine overreaching hepcidin
2015/5/15
The purpose of the present study was to verify whether impaired iron metabolism in young athletes is a consequence of an excessive workload during the tournament season. Low levels of ferritin (under ...
利用同源克隆的方法从鲢（Hypophthalmichthys molitrix）的肝脏中克隆出抗菌肽Hepcidin cDNA（GenBank登入号KF312213）后，通过pET32a（+）构建含抗菌肽Hepcidin的重组质粒的pET-Hep/Rosetta菌株，在37 ℃、28 ℃和16 ℃下分别用0.5 mmol•L-1和1.0 mmol•L-1 IPTG诱导表达，...
研究维持性血液透析（MHD）红细胞生成素（EPO）抵抗患者pro-hepcidin与炎性反应和铁代谢的关系。 方法 40例MHD患者为研究对象，其中20例EPO低反应和20例EPO正常反应。20例健康体检者为对照组。检测参试者的血红细胞计数（RBC）、血红蛋白（Hb）、网织红细胞计数（Ret）、红细胞比容（Hct）、血清铁蛋白（SF）、转铁蛋白（TF）、血清铁和总铁结合力、转铁蛋白饱和度（TSAT...
以大黄鱼（Pseudosciaena crocea）管家基因18S rRNA和βactin作为内参基因，分别比较2个内参基因建立的相对定量曲线，最终确立以18S rRNA为参比基因，定量分析大黄鱼的Hepcidin抗菌肽基因.该相对定量分析方法所得结果与Northern-blot方法一致.应用建立的Hepcidin基因的实时荧光相对定量研究方法，对大黄鱼头肾中的Hepcidin基因转录物进行相对...
本试验旨在研究铁过量或缺乏对新生仔猪血清生化指标及肝脏hepcidin mRNA表达量的影响。挑选新出生的"杜长大"三元杂交仔猪15头,随机分为3组,即缺铁组、正常组和铁过量组,每组5个重复,每个重复1头猪。3和7日龄时,缺铁组分别注射1 mL生理盐水,正常组分别注射1 mL右旋糖酐铁(含铁150 mg),铁过量组分别注射3 mL右旋糖酐铁(含铁450 mg)。7日龄时,将所有仔猪全部处死,采集血...
Hepcidin（ Hepc）是一类性质独特的抗菌肽，具有广谱的抗革兰氏阳性、阴性细菌和真菌等作用。利用RT唱
PCR 和RACE 等技术，从经过多种细菌攻毒的花鲈（ Lateolabrax japonicus）肝组织中克隆出Hepc 全长cDNA ，命名为Hepc２ ，Genbank 登录号为AY６０４１９５ 。Hepc２ 有５８１ 个碱基，其中阅读框有２５８ 个碱基，编码８６ 个氨基酸。预测...
Ferroportin１是重要的跨膜铁输出分子，主要分布于十二指肠和单核巨噬系统的细胞膜上，参与机体的肠铁吸收和巨噬细胞对铁的再循环等过程。Hepcidin是调节机体铁代谢平衡的激素，机体通过肝脏分泌的hepcidin对铁转运相关蛋白表达的调控实现机体自身的铁稳态。最新研究显示，ferroportin１有可能是hepcidin的靶分子。hepcidin直接作用于ferroportin１，引起fer...