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An integrative systems biology approach for analyzing liver hypermetabolism
hypermetabolism gene expression regulation
2009/12/24
Severe injury and other disease conditions (cancer, diabetes) lead to a hypermetabolic
state featuring increased turnover of proteins, fatty acids and carbohydrates. Prolonged
hypermetabolism is a...
Circadian variations in liver gene expression: Relationships to drug action
Circadian variations liver gene expression drug action
2009/12/24
Chronopharmacology is an important but under-explored aspect of therapeutics. Rhythmic
variations in biological processes can influence drug action, including pharmacodynamic
responses, due to ci...
Three-Dimensional Model for Determining Inhomogeneous Thermal Dosage in a Liver Tumor During Arterial Embolization Hyperthermia Incorporating Magnetic Nanoparticles
Arterial embolization hyperthermia magnetic nanoparticles mathematical modeling specific absorption
2010/7/16
Hyperthermia treatment incorporating magnetic nanoparticles (MNPs) is a hopeful therapy for cancers. Acquiring information about the MNPs’ deposition in tumor tissues and modeling magnetic heating in ...
Acute stress augments innate immunity in the liver and increases hyaluronan levels in the tissues and blood of mice
increases hyaluronan levels blood of mice
2009/12/16
The effect of acute stress on the immune system was examined in mice. Restraint stress decreased the number of lymphocytes in the liver, whereas the number of lymphocytes remained unchanged in the spl...