搜索结果: 1-15 共查到“生物医学工程 biology”相关记录17条 . 查询时间(0.125 秒)
氮素是植物生长发育所需的大量营养元素，也是作物产量的主要限制因素之一。尽管氮元素在大气中含量丰富，但是不能直接被植物吸收利用，而豆科植物可以通过与根瘤菌共生将氮气转化为植物可直接利用的含氮化合物。根瘤作为共生固氮的场所，为根瘤菌提供固氮的微环境和能量。因此，根瘤器官的发育调控机制是共生固氮研究中最重要的科学问题之一。
浙江大学生命科学研究院2022年5月2日徐平龙实验室在Nature Cell Biology发文鉴定首条非经典cGAS-STING通路及其控制蛋白质合成和器官纤维化病变的关键功能（图）
徐平龙 非经典cGAS-STING通路 蛋白质合成 器官纤维化病变
2022/10/25
2022年5月2日，浙江大学生命科学研究院徐平龙实验室在Nature Cell Biology上在线发表了题为“A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis”的研究长文，鉴定了一条物种进化上非常古老的cG...
无义介导的RNA降解（Nonsense-mediated decay, NMD）是真核生物一种重要的mRNA质量控制方式，细胞通过检验终止密码子与最后一个剪接接头的距离是否超过55nt来判断该终止密码子是否为提前终止密码子（Premature Termination Codon, PTC）从而决定是否降解该RNA。因此经典的NMD通路是一种RNA剪接依赖的机制。假基因是一种失去了蛋白编码能力或者表...
南方科技大学贾宁等在Nature Reviews Molecular Cell Biology 发表anti-CRISPR 作用机制的综述文章（图）
细菌；CRISPR-Cas ；噬菌体
2021/10/13
近日，南方科技大学医学院助理教授贾宁在Nature Reviews Molecular Cell Biology在线发表题为“Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins”的综述文章，系统阐述了病毒anti-CRISPR 蛋白逃逸细菌CRISPR-Cas免疫系...
第十四届生物医学光子学与成像技术国际学术研讨会（The 14th International Conference on Photonics and Imaging in Biology and Medicine,PIBM 2017）
第十四届 生物医学光子学与成像技术 国际学术研讨会
2017/7/17
PIBM is the largest series international biomedical photonics conference in Asia. PIBM was suggested by Dr. Britton Chance and was initially held at HUST biyearly since 1999. PIBM is designed to bring...
北京大学生命科学学院伊成器研究组在Nature Chemical Biology上报道全转录组假尿嘧啶RNA修饰谱图（图）
北京大学生命科学学院 伊成器研究组 Nature Chemical Biology 假尿嘧啶RNA修饰谱图
2015/6/18
2015年6月15日，北京大学生命科学学院伊成器研究组在Nature Chemical Biology杂志在线发表题为“Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome”的研究论文（DOI:10.1038/nchembio.1836）。文章报道了一种通过化学标记和富集手段实现全转录组...
Nature Structural & Molecular Biology发表中国科学院生物物理研究所肉碱膜转运蛋白CaiT三维结构研究成果（图）
Nature Structural & Molecular Biology 膜转运蛋白CaiT
2010/4/1
2010年3月28日，生物物理研究所江涛研究员课题组在 Nature Structural & Molecular Biology杂志在线发表了题为“Crystal Structure of the Carnitine Transporter and Insights into the Antiport Mechanism ”的文章。该研究解析了肉碱膜转运蛋白CaiT的三维结构，并对其分子机制进行...
Dr.Michael Levin，Professor and Director of Tufts Center for Regenerative and Developmental Biology（图）
Michael Levin Professor Regenerative and Developmental Biology Genetics
2010/1/4
Dr.Michael Levin study these processes in the context of embryonic development and regeneration, with a particular focus on the biophysics of cell behavior. In contrast to other groups focusing on gen...
An integrative systems biology approach for analyzing liver hypermetabolism
hypermetabolism gene expression regulation
2009/12/24
Severe injury and other disease conditions (cancer, diabetes) lead to a hypermetabolic
state featuring increased turnover of proteins, fatty acids and carbohydrates. Prolonged
hypermetabolism is a...
Networks, Biology and Systems Engineering: A Case Study in Inflammation
Systems biology transcriptional regulation disease models inflammation
2009/12/24
Biological systems can be modeled as networks of interacting components across multiple scales. A central problem in computational systems biology is to identify those critical components and the rule...
Janes Uses Engineering Approach to Investigate Cancer's Biology
Engineering Approach Cancer's Biology
2009/12/17
In the past year, University of Virginia biomedical engineer Kevin Janes has won $2.6 million in no-strings-attached funding for his innovative research to better understand how cells "make decisions"...
Chemical and Biological Studies for the Molecular Mechanisms of Human Trivalent Dimethylarsenic Metabolite-Induced Cytolethality;Chemical Biology of Arsenicals
arsenic arsenite dimethylarsenic trivalent dimethylarsenic dimethylarsinous GSH chemical biology
2009/3/23
Although inorganic arsenicals are toxic and carcinogenic in humans, inorganic arsenite (AsIII) has recently emerged as a highly effective chemotherapeutic agent for acute promyelocytic leukemia (APL)....
Medical imaging and physiological modelling: linking physics and biology
Medical imaging physiological modelling physics and biology
2010/2/25
Medical image analysis is increasingly providing a sophisticated set of tools for processing measurement inputs into clinically relevant outputs, although this is, on the whole, completed without cons...
Review of "System Modeling in Cellular Biology: From Concepts to Nuts and Bolts" by Szallasi, Stelling and Periwal
System Modeling Cellular Biology Nuts and Bolts
2010/2/26
"System Modeling in Cellular Biology: From Concepts to Nuts and Bolts" by Szallasi, Stelling and Periwal introduces the relevant concepts, terminology, and techniques of this field of science. It emph...
Review of "Stochastic Modelling for Systems Biology" by Darren Wilkinson
Stochastic Modelling Systems Biology Darren Wilkinson
2010/2/26
"Stochastic Modelling for Systems Biology" by Darren Wilkinson introduces the peculiarities of stochastic modelling in biology. This book is particularly suited to as a textbook or for self-study, and...