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We studied healthy full-term infants (n = 42) born after normal pregnancies and deliveries. All infants had a family history of atopy (both parents or one of the parents and a sibling had atopic sy...
Animal products contribute significantly to the saturated fat and cholesterol content of the American diet. Contrary to dietary advice, consumers have not limited their consumption of animal produc...
Animal studies showed that dietary flaxseed oil [rich in the n3 polyunsaturated fatty acid -linolenic acid (ALA)], evening primrose oil [rich in the n6 polyunsaturated fatty acid -linolenic acid (...
The fatty acids arachidonic acid (AA; 20:4n26) and docosahexaenoic acid (DHA; 22:6n23) are essential for fetal growth and development, but their metabolism may be altered in insulin resistance
Preeclampsia is characterized by enhanced platelet aggregation and vasoconstriction and is related to an elevated ratio of thromboxane A2 to prostacyclin I2.
Elevated plasma triacylglycerol concentrations have been associated with increased risk of coronary heart disease (CHD). In the past, the epidemiologic evidence about the causal role of triacylglyc...
Background:Evidence from observational studies suggests that there is an association between n–3 long-chain polyunsaturated fatty acids and depression; however, this association has yet to be examined...
Background: Docosahexaenoic acid (DHA) and arachidonic acid (AA) are long-chain polyunsaturated fatty acids (LCPs) that play pivotal roles in growth and neurodevelopment.Objective: We aimed to quantif...
Background: Information is lacking on the potential effect of n–3 polyunsaturated fatty acids (PUFAs) on the adipose tissue of patients with type 2 diabetes.Objective: We evaluated whether n–3 PUFAs h...
Background: Plasma lipoproteins may be classified by their apolipoprotein composition. The lipoprotein subclass containing apolipoproteins B and C (LpB:C) is considered the most atherogenic.Objective:...
The Jewish population of Israel consumes a diet rich in n−6 polyunsaturated fatty acids (PUFAs), principally linoleic acid. The consequences of this diet for ischemic heart disease (IHD) remain ...
Dietary α-linolenic acid (ALA) can be converted to long-chain n−3 polyunsaturated fatty acids (PUFAs) in humans and may reproduce some of the beneficial effects of eicosapentaenoic acid (EPA) an...
Fetal growth requires n−3 docosahexaenoic acid (DHA), which is derived from the essential n−3 fatty acids in the maternal diet. DHA is accumulated in the developing brain and is critical f...
Little is known about the relation of the dietary intake of n−3 polyunsaturated fatty acids, ie, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) from fatty fish and α-linolenic acid f...
The rationale for expecting a benefit from ALA is that it is the metabolic precursor of EPA and DHA. The extent of its conversion is controversial, however, even among investigators using similar trac...

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