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Cyclophosphamide in the male rat：new pattern of anomalies in the third generation
Cyclophosphamide male rat anomalies third generation
2009/2/23
Several abnormalities, such as postnatal deaths and behavioral impairments, have been previously reported in the progeny of male rats exposed to the cytostatic drug cyclophosphamide 60 days prior to...
Analysis of the relationship between defective sperm function and the generation of reactive oxygen species in cases of oligozoospermia
defective sperm function reactive oxygen species oligozoospermia
2009/2/23
The ability of human spermatozoa to exhibit sperm-oocyte fusion in response to the ionophore, A23187, was examined in relation to the capacity of these cells to generate reactive oxygen species. I...
Antimitotic drugs in the male rat. Behavioral abnormalities in the second generation
Antimitotic drugs male rat Behavioral abnormalities second generation
2009/2/23
The second generation descended from rats treated either with cyclophosphamide alone or with both cyclophosphamide and vinblastine were investigated. As in the first generation, the offspring were...
Three-generation evaluation of Y-chromosome microdeletion
Three-generation evaluation Y-chromosome microdeletion
2009/2/18
Sperm cells can be retrieved directly from the testis (testicular sperm extraction [TESE] procedure) and used for intracytoplasmic sperm injection (ICSI), circumventing underlying spermatogenetic ...
Efficient Generation of Transgenic Rats Through the Male Germline Using Lentiviral Transduction and Transplantation of Spermatogonial Stem Cells
lentivirus spermatogenesis testis
2008/12/24
Spermatozoa produced from spermatogonial stem cells (SSCs) are the vehicle by which genes of a male are passed to the next generation. A single SSC has the ability to self-renew and produce thous...
Combining Our Strengths:Training the Next Generation of Sexuality Researchers
Strengths Sexuality Researchers
2008/6/13
A number of serious challenges to the physical and mental health of the US
population confront us. Several of these involve sexuality. These challenges
include the following:
✤ More than one...