搜索结果: 1-8 共查到“医学遗传学 Genes”相关记录8条 . 查询时间(0.046 秒)
Expression of Testis Specific Genes TSGA10,TEX101 and ODF3 in Breast Cancer
Testis Gene TSGA10 TEX101 ODF3 Breast Cancer
2015/9/28
Background: Breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. Cancer...
University of Queensland researchers have been part of a major breakthrough in understanding the cause of the debilitating arthritic condition ankylosing spondylitis (AS).
The research, led by Profe...
Effects of the N-Ras Oncogene on the Expression of Other Cellular Genes in CO25 Myoblast Cells
oncogene myoblast ras myc differentiation
2009/7/3
The effects of the N- ras oncogene on the transcription levels of c- myc, p53, c-K-ras and b-actin genes have been investigated by Northern blotting in a cell line which normally differentiates into m...
Expression Analysis of DEK, AF4 and FLI1 Genes in All-Trans-Retinoic Acid (ATRA) Treated Acute Promyelocytic Leukaemia t(15;17) Patients by Quantitative Real-Time PCR
DEK AF4 FLI1 Acute Promyelocytic Leukemia All-Trans-Retimic Acid
2009/6/23
All-trans retinoic acid (ATRA) sensitivity of acute promyelocytic leukaemia (APL) cells is strictly dependent on the presence of t(15;17), but the molecular background of this sensitivity remains obsc...
No Evidence for Association between Amelogenesis Imperfecta and Candidate Genes
Amelogenesis Imperfecta KLK4 Polymorphism Consanguineous marriages
2009/12/16
Background: Amelogenesis imperfecta (AI) is an inherited tooth disorder. Despite the fact that up to now, several gene mutations in MMP20, ENAM, AMELX and KLK4 genes have been reported to be asso...
Various Expression Patterns of α1 and α2 Genes in IgA Deficiency
gene expression IgA subclasses partial IgA deficiency selective IgA deficiency α1 gene deletion
2010/11/16
Background: IgA deficiency (IgAD) is the most common immunodeficiency, however the pathogenesis in most cases of IgAD is unknown. There are 2 subclasses of IgA, IgA1 and IgA2, and its heavy chains are...
南京汉族群体肺癌易感性相关基因的研究Studies of the Genes Related to Lung Cancer Susceptibility in Nanjing Han Population, China
肺癌 代谢酶基因 多态性 遗传易感性
2008/1/8
摘要
为了探讨南京汉族群体肺癌易感性相关基因，我们采用1:1病例对照研究方法，以PCR—RFLP技术检测了152对肺癌和健康对照的CYP1A1、CYP2E1、GSTM1、GSTT1、GSTP1、mEH和NQO1基因的基因型并分析其与肺癌的相关性。结果发现携带CYP1A1突变基因型（wt/mt和mt/mt）的个体明显增加患肺鳞癌的风险(OR=2.31,95%CI=1.23-4.36)；GSTT1（...
摘要阿尔茨海默类痴呆（AD）是老年痴呆中最常见的一种,它以渐进性的神经功能退化并伴随着整体认知能力的下降为特征。早发性AD主要是由β-淀粉样前体蛋白（APP）基因和早老素基因突变引起，而与晚发性AD发病明显相关的只有载脂蛋白E-ε4 ( APOE-ε4)等位基因。但是APOE-ε4等位基因对AD发病既非充分又非必要，而且只能解释少于50%的AD的遗传变异。所以有必要进一步寻找与AD的关联基因。
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