搜索结果: 1-15 共查到“基础医学 interleukin-4”相关记录16条 . 查询时间(0.178 秒)
Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
上海交通大学基础医学院王宏林课题组发现Interleukin-6通过作用于电压门控钙离子通道来调节间充质干细胞迁移的新机制
王宏林课题组 Interleukin-6 电压门控钙离子通道 间充质干细胞 迁移机制
2014/7/16
近日，国际学术期刊《Stem Cells》在线发表了上海交通大学基础医学院/上海市免疫学研究所王宏林课题组题为“Autocrine Interleukin-6 Drives Skin-Derived Mesenchymal Stem Cell Trafficking via Regulating Voltage-Gated Ca2+ Channels”的研究论文，报道了自分泌的IL-6在MSCs（...
Interleukin-12 and Tumor Necrosis Factor-Β Gene Polymorphisms as Genetic Susceptibility Factors for Brucellosis in Iranian Patients
Brucella Genetic polymorphisms Interleukin-12 Tumor necrosis factor-β Iran
2015/9/21
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Production and Purification of Monoclonal Antibodies to Human Interleukin-2 and Their Use for Immunoaffinity Purification of Recombinant Human Interleukin-2
Monoclonal antibody human interleukin-2 immunoaffinity purification
2009/6/26
Monoclonal antibodies (mAbs) are a powerful immunochemical tool. Today, the availability of mAbs with desired specificity enables ligand separation based upon the immunoaffinity technique. By using th...
Aim: The objectives of this study were to compare interleukin-6 (IL-6) and nitric oxide (NO) levels in newborns with culture-proven sepsis with levels in age- and gestational age (GA)-matched controls...
Associations between low back pain,disability,functional status,and serum interleukin-1 b level
Low back pain interleukin-1 b functional status
2010/1/12
Aim: In the past the role of biochemical mediators of inflammation in back pain received little attention. The purpose of the present study was to examine the association between serum IL-1 b level in...
House Dust Mite Extract Induces Interleukin-9 Expression in Human Eosinophils
allergens eosinophils house dust mites interleukin-9 proteinase activated receptor 2
2010/11/17
Accumulated eosinophils in the airways in asthma may directly react with HDM and produce IL-9 to further promote Th2-type immune responses. Protease-activated receptor 2, a ligand for serine proteases...
Interleukin-4 and interleukin-13 induce fibronectin production by human lung fibroblasts
fibronectin human lung fibroblast interleukin-4 interleukin-13 remodeling
2010/11/25
The results showed that IL-4 and IL-13 induced fibronectin production in a time- and a concentration-dependent manner. Anti-transforming growth factor (TGF)-β1 antibody (ab) inhibited TGF-β1-induced f...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
Blocking the CD154-CD40 interaction with anti-CD154 antibody differentially regulates interleukin-4 synthesis in T cells and IgE production in B cells
CD154 CD40 germline Cε IgE interleukin-4
2010/11/25
Using severe combined immunodeficiency mice engrafted with peripheral blood mononuclear cells from atopic patients, we analyzed the regulatory effects of anti-CD154 antibody on the in vivo induction o...
Neutrophils, interleukin-17 and obstructive airway disease
airway inflammation asthma chemokine chronic obstructive pulmonary disease cytokine eosinophil macrophage protease T lymphocyte
2010/11/24
There is increasing evidence that an exaggerated accumulation of activated neutrophils is linked to the clinical course of obstructive airway diseases, such as asthma and chronic obstructive pulmonary...
Structural and functional analysis of a new cytokine, ML-1 (interleukin-17F)
airway inflammation cytokine network interleukin-17 family mitogen-activated protein kinase
2010/11/24
Recent large-scale sequencing of the human genome has facilitated novel gene discovery. A novel gene, ML-1 (interleukin (IL)-17F), was identified from a human expressed sequence tag (EST) sequence, a ...
Inhibition of nasal mucosal eosinophils after immunotherapy is associated with a decrease in interleukin-13 mRNA and vascular cell adhesion molecule-1 expression
adhesion molecule allergic rhinitis apoptosis immunotherapy interleukin-13
2010/11/22
Analysis of the clinical data confirmed that the proportion of patients who showed greater than 60% improvement in symptoms (47 and 15%) and in rescue medication (79 and 10%) were significant for the ...
Prostaglandin D2 and interleukin-5 reduce CRTH2 surface expression on human eosinophils
CRTH2 eosinophils interferon-γ interleukin-4 interleukin-5 prostaglandin D2
2010/11/22
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified. Because PGD2 was reported to have chemotac...
Short-term stimulation with interleukin (IL)-4 enhances purified protein derivative-induced production of an eosinophil chemotactic lymphokine, but suppresses IL-5 production
eosinophil chemotactic lymphokine granulocyte—macrophage colony stimulating factor interferon-γ interleukin-4 interleukin-5 RANTES
2010/11/29
The effect of interleukin (IL)-4 on eosinophil chemotactic lymphokine (ECL) production from peripheral blood mononuclear cells (PBMC) stimulated with purified protein derivative (PPD) was examined. Th...