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The Oncolytic Effect of Respiratory Syncytial Virus (RSV) in Human Skin Cancer Cell Line, A431
Oncolytic Viruses Apoptosis Skin Neoplasms Flow Cytometry
2015/9/29
Background: Oncolytic viruses have become of noticeable interest as a novel biological approach for selectively infecting cancer cells and triggering apoptosis in a number of malignant cells. Many res...
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
DNA repair gene therapy
2014/12/12
Reactive oxygen species (ROS) have been implicated as one of the agents responsible for many neurodegenerative diseases. A critical target for ROS is DNA. Most oxidative stress-induced DNA damage in t...
Influence of Preservation Solutions and Bile on a Human Bile Duct Epithelium Cell Line: An In-Vitro Study
Organ Preservation Liver Transplantation Bile Duct Epithelium In Vitro
2013/1/31
Introduction: Bile duct complications are common after liver transplantation. The impact of preservation solution is unclear. Aim: We investigated the impact of different preservation solutions with a...
Urginea maritima (L.) Baker (Liliaceae) extract induces more cytotoxicity than standard chemotherapeutics in the A549 non-small cell lung cancer (NSCLC) cell line
Urginea maritima cytotoxicity apoptosis MTT non-small cell lung cancer
2011/3/22
Urginea maritima (Um) is a plant native to especially Turkey and the Mediterranean area. In this study, we investigated whether Um extract exerted cytotoxicity on cancer cells. Materials and methods: ...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Titanium Surface Roughness Accelerates RANKL-dependent Differentiation in the Osteoclast Precursor Cell Line,RAW264.7
Titanium Osteoclast Implant
2009/9/14
The present study was a molecular analysis of the initial differentiation of osteoclast precursor RAW264.7 cells on titanium specimens. RAW264.7 cell line was cultured on titanium specimens of which t...
IN VIVO AND IN VITRO ANTITUMOR EFFECT OF NUTRIENT SYNERGY ON HUMAN OSTEOSARCOMA CELL LINE MNNG-HOS
Ascorbic acid epigallocatechin gallate lysine Matrigel invasion MMP MNNG-HOS nude mice nutrient synergy osteosarcoma prognosis proline treatment
2009/7/15
Current treatment of osteosarcoma is associated with poor prognosis, especially due to the increased risk of developing other cancers with chemotherapy. Therefore, new safe effective treatment strateg...
Specific Antitumor Effects of Tumor Vaccine Produced by Electrofusion between Osteosarcoma Cell Line and Dendritic Cells in Rats
Dendritic cell osteosarcoma tumor vaccine
2009/7/15
Background: Dendritic cells (DCs) are the strongest antigen presenting cells (APCs). They can present antigen to T lymphocytes in vivo and in vitro, and induce cytotoxic T lymphocyte (CTL) reactions. ...
DNase γ-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line
DNase γ-dependent -independent apoptotic DNA
2009/12/16
DNA fragmentation is a biochemical hallmark of apoptosis. Several endonucleases, including CAD/DFF40 and endonuclease G, are implicated in DNA fragmentation. DNase γ has also been considered to be one...
Arsenic Trioxide Has Additive Cytotoxic Effects on MCF-7 Breast Cancer Cell Line With Taxanes
breast cancer MCF-7 arsenic trioxide docetaxel paclitaxel
2009/6/25
Breast cancer is the most prevalent cancer in women and an important cause of both morbidity and mortality. Although long-term disease-free survival is offered to women with early stage disease by cur...
Vitamin D Dependent Down Regulation of Arf1 Gene in Human Leukemia Cell Line HL-60
Gene expression ARF1 Vitamin D Real-Time RT-PCR
2009/6/24
ADP-ribosylation factor 1 (ARF1) is a gene belonging to the ARF gene family. ARF genes, small guanine nucleotide-binding proteins, constitute a family of the RAS superfamily. This superfamily function...
Cytotoxicity of Low Dose Epirubicin-HCI Combined with Lymphokine Activated Killer Cells Against Hepatocellular Carcinoma Cell Line Hepatoma G2
Hepatoma epirubicin-HCI cytotoxicity enzymes
2009/6/23
Recent evidance supports the concept that Epirubicin-HCI and Lymphokine-activated killer cells (LAK) cytotoxicity may be mediated by free radical and oxyradical generation. We tested this hypothesis f...
Comparative Cytotoxicity of Fludarabine in Human Peripheral Blood Mononuclear Cells and in the Promyelocytic Leukemia Cell Line (HL60)
HL60 MTT assay fludarabine cytotoxicity differentiation
2009/6/23
Fludarabine is an inhibitor of DNA/RNA synthesis with antitumor activity on lymphoproliferative malignancies. We investigated the dose-dependent cytotoxic effects of the drug on human peripheral blood...
Pressure antagonism of nitrous oxide depression of intracellular calcium in a neuroblastoma cell line
human Pressure antagonism nitrous oxide
2009/6/8
While the ability of increased pressure to reverse anaesthesia has been well documented, the cellular or molecular mechanism(s) responsible for their mutual antagonism have remained elusive.
Effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and proliferation of HO-8910 cell line of ovarian cancer
3`-azido-3`-deoxythymidine (AZT) reverse transcriptase inhibitor telomerase proliferation ovarian carcinoma cell
2009/4/20
Objective: To study the effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and the proliferation of ovarian cancer cells in vitro. Methods: Telomerase activity was detected by enzyme ...