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Cellular Derivatives and Efficacy in Wound and Scar Management
Biological Wound Healing Scars Cell-Free Derivatives
2013/1/29
Biologicals have been used for decades in biopharmaceutical topical preparations. Because cellular therapies are routinely used in the clinic they have gained significant attention. Different derivati...
Synthesis and Influence of Two Quinoxalinone Derivatives on Anxiety- and Depressive-Like Responses in Wistar Rat
Depression Anxiety Quinoxalinone Derivatives Locomotor Activity Wistar Rats
2013/1/30
Two new quinoxalinone derivatives have been synthesized adopting the HONG method, and investigated for some neuropharmacological effects (anxiety- and depressive-like responses) in rats. The present e...
Synthesis of metronidazole derivatives as antigiardiasis agents
Metronidazole Giardiasis Imidazole Epoxide
2010/4/6
Metronidazole (MTZ) and its derivatives have been extensively used to treat infections caused by protozoa and anaerobic bacteria. In this investigation several novel imidazole and nitroimidazol deriva...
Synthesis and smooth muscle Calcium channel antagonist effects of new derivatives of 1,4-Dihydropyridine containing Nitroimidazol substituent
Dihydropyridine Calcium channels antagonist GPILSM
2009/12/29
A group of racemic 3-[(2-hydroxyethyl), (2-Methoxyethyl), (2-acetylethyl) or (2-cyanoethyl)], 5- methyl, ethyl or isopropyl-1, 4-dihydro-2, 6-dimethyl-4-(1-methyl-5-nitro-2-imidazolyl)-3, 5-pyridinedi...
UV-VIS spectra and photoinitiation behaviors of acylphosphine oxide and bisacylphosphine oxide derivatives in unfilled, light-cured dental resins
UV-VIS spectra Photo-DSC Degree of conversion
2009/9/14
The aims of this study were to investigate the photoinitiation behaviors of acylphosphine oxide (APO) and bisacylphosphine oxide (BAPO) derivatives in comparison to D,L-camphorquinone (CQ)/tertiary am...
New Matrix Polymers for Photo-activated Resin Composites using Di-α-fluoroacrylic Acid Derivatives
Polymerization Resin composite Fluorine-substituted monomer
2009/9/11
A novel matrix resin for photo-activated resin composites was developed using α-fluoroacrylic acid derivatives. To render resin composites with improved mechanical properties, silica fillers were also...
In Vivo Evaluation of the Nitroimidazole-Based Thioflavin-T Derivatives as Cerebral Ischemia Markers
Nitroimidazole-Based Thioflavin-T Derivatives Cerebral Ischemia Markers
2009/9/7
Timely imaging and accurate interpretation of cerebral ischemia are required to identify patients who might benefit from more aggressive therapy, and nuclear medicine offers a noninvasive method for d...
Sensitivity to CPT-11 and platinum derivatives of stage II/III node-positive gastric cancer with occult neoplastic cells in lymph node sinuses
Gastric cancer occult neoplastic cells CPT-11 Topoisomelase-1 inhibitor platinum agents Bax ERCC-1 isolated tumor cells
2009/7/15
In this study, immunohistochemistry was used to detect Topo-1 and Bax/ERCC-1 expression in patients who had lymph node metastasis of stage II/III gastric cancer with occult neoplastic cells (ONCs) in ...
Evaluation of Cytotoxic Potential of Newly Synthesized Antiviral Aminopyrazoloquinoline Derivatives
aminopyrazoloquinoline apoptosis DNA damage MCF-7 MDA-MB-231
2009/4/20
In the present study, we screened newly synthesized antiviral aminopyrazoloquinoline derivatives for cytotoxic potential in human normal and breast cancer cell lines using apoptosis as biomarker....
Zinc（II）complexes with allixin-derivatives as oral therapeutics for type 2 diabetes
complex allixin in vitro insulin-mimetic effect anti-diabetic effect KKAy mice
2009/3/23
During the investigation on the development of Zn(II) complexes with a blood glucose-lowering effect in experimental diabetic animals, we found a potent bis(maltolato)Zn(II) complex (Zn(ma)2) which ex...
Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity
vitamin D3 type-1 cellular immunity
2009/3/2
1α,25-dihydroxyvitamin D3 [Calcitriol or 1,25(OH)2D3] is an important active metabolite involved in multiple functions but its calcemic effect in vivo limits its therapeutic applications. On the oth...
专著信息
书名
Trifluoromethylation of flavonoids and anti-tumor activity of the trifluoromethylated flavonoid derivatives
语种
英文
撰写或编译
作者
Cai-Ling Wang,Hong-Qi Li,Wei-Dong Meng,Feng-Ling Qing
第一作者单位
出版社
Bioo...
期刊信息
篇名
(2)α,α-Trehalose derivatives bearing guanidine groups as inhibitors to HIV-1 Tat-TAR RNA interaction in human cells.
语种
英文
撰写或编译
作者
王敏,杨铭
第一作者单位
刊物名称
Bioorganic & Medicinal Chemistry Letters
页...
SYNTHESIS AND ANTICONVULSANT ACTIVITY OF NOVEL 2-AMINO-5-[4-CHLORO-2-(2-CHLOROPHENOXY) PHENYL]-1,3,4-THIADIAZOLE DERIVATIVES
1,3,4-thiadiazole Anticonvulsant activity Maximal electroshock
2010/4/9
Several novel 2-amino-5-[4-chloro-2-(2-chlorophenoxy)phenyl]-1,3,4-thiadiazole derivatives 4a-d were synthesized and their anticonvulsant activity was determined by evaluation of the ability of theses...