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Speeding up Tandem Mass Spectrometry Based Database Searching by Peptide and Spectrum Indexing
Mass Spectrometry Database Searching Peptide Spectrum Indexing
2010/12/21
Database searching is the technique of choice for shotgun proteomics, and to date much research effort has been spent on improving its effectiveness. However, database searching faces a serious challe...
Exploiting the kernel trick to correlate fragment ions for peptide identification via tandem mass spectrometry,
correlate fragment ions peptide identification tandem mass spectrometry
2010/12/14
The correlation among fragment ions in a tandem mass spectrum is crucial in reducing stochastic mismatches
for peptide identification by database searching. Until now, an efficient scoring algorithm ...