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周玉峰团队在《Journal of Allergy and Clinical Immunology》首次揭示环状RNA在过敏性皮炎和银屑病中的功能及调控机制（图）
周玉峰团队 环状RNA 银屑病 过敏性皮炎
2023/4/14
过敏性皮炎（atopic dermatitis，AD）也称特应性皮炎，是一种慢性复发性的皮肤炎症性疾病，发病率在儿童中高达20-30%，成人为3-10%。主要临床表现为皮肤屏障功能受损、瘙痒和慢性皮肤炎症。AD的病因复杂，病情迁延不愈，极大地影响了患者的生活质量。近年来的研究表明除遗传因素外，环境和表观遗传学因素也在一定程度上影响着AD的发病过程。此外，“过敏性进程”理论揭示婴幼儿期的AD有可能随...
The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids
absorption ADME flavonoids genotype health metabolism microbiome
2018/11/12
At a population level, there is growing evidence of the beneficial effects of dietary flavonoids on health. However, there is extensive heterogeneity in the response to increased intake, which is like...
第四届生殖免疫学术新进展研讨会（International Forum on Reproduction and Autoimmunity (2017)-4th New Trends in Clinical and Basic Research on Reproductive Immunology）
第四届 生殖免疫学术新进展 研讨会
2017/8/31
由国际自身免疫协会、深圳中山泌尿外科医院以及成都西囡妇科医院联合主办的“2017中国深圳 ∙ 国际生殖与自身免疫高峰论坛——第四届生殖免疫学术新进展研讨会”将于2017年10月20日-21日在深圳召开。此次会议旨在增加各位同仁之间关于生殖免疫新进展的学习和交流，促进我国生殖免疫学基础研究及临床应用的发展。会议有幸邀请到国内外知名专家和学者，分别就免疫及生殖免疫前沿进展、自身免疫与生殖失...
Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial
α-carboxyethyl hydroxychromanol α-CEHC α-carboxymethylbutyl
2018/11/13
Background: Vitamin E supplementation improves liver histology in patients with nonalcoholic steatohepatitis, which is a manifestation of the metabolic syndrome (MetS). We reported previously that α-t...
Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial
energy metabolism epigallocatechin-3-gallate multiple sclerosis sex difference calorimetry microdialysis
2018/12/24
Background: Muscle weakness and fatigue are common symptoms in multiple sclerosis (MS). Green tea catechins such as (−)epigallocatechin-3-gallate (EGCG) are known to improve energy metabolism at...