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One reason it's so difficult to produce effective vaccines against some viruses, including influenza and HIV, is that these viruses mutate very rapidly. Mutation allows them to evade the antibodies ge...
Effects of Heat Stress on Somatostatin and Some Related Immune Factors in the Small Intestine of Wenchang Chicks
hyperthermia somatostatin intestinal mucosa cytokines lysozyme activity
2018/3/5
To investigate the effects of heat stress (HS) on developmental changes in immune functions of chick intestinal
mucosa, one-day-old broiler chicks were randomly assigned into control check (CK) and h...
How do T cells, the beat cops of the immune system, detect signs of disease without the benefit of eyes? Like most cells, they explore their surroundings through direct physical contact, but how T cel...
Tiny tech reprograms immune cells to fight cancer
Tiny tech reprograms immune cells fight cancer
2017/4/27
Dr. Matthias Stephan has a bold vision. He imagines a future where patients with leukemia could be treated as early as the day they are diagnosed with cellular immunotherapy that’s available in their ...
UCLA scientists show how to amplify or stifle signals for immune responses
UCLA scientists amplify stifle signals immune responses
2017/3/30
T cells, the managers of our immune systems, spend their days shaking hands with another type of cell that presents small pieces of protein from pathogens or cancerous cells to the T cell. But each T ...
Humoral and cellular immune response to Histophilus somni recombinant heat shock protein 60 kDa in farm animals
rHsp60 Histophilus somni subunit vaccine calves piglets hens
2015/11/26
The aim of this study was to evaluate the effects of immunising farm animals with the Histophilus somni recombinant heat shock protein 60kDa (H. somni rHsp60) in field conditions. Fifty piglets, 10 ca...
The effect of dominant negative EGR-1 and hyperbaric oxygen on immune cell apoptosis
Induction of cells and multicellular organisms physiology cell death cell research gene regulation
2014/12/11
The ultimate means of limiting the influence of an individual cell on the physiology of a multicellular organism is to induce the death of that cell. Apoptosis is a genetically regulated form of cell ...
“Recent research has found that cancer is already adept at using cyberwarfare against the immune system, and we studied the interplay between cancer and the immune system to see how we might turn the ...
Experiments prove 'stemness' of individual immune memory cells
Experiments prove stemness individual immune memory cells
2014/8/14
Researchers in Germany and the U.S. have proven for the first time that specific individual cells of the immune system, termed central memory T cells, have all the essential characteristics of adult t...
Immune system drives pregnancy complications after fetal surgery in mice(图)
Immune system drives pregnancy complications
2014/3/18
As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature b...
Plasmodium knowlesi H strain pregnancy malaria immune responses in olive baboons (Papio anubis)
Baboon pregnancy malaria cytokine proliferation
2012/4/28
Approximately 24 million pregnant women in Sub-Saharan Africa are at risk of suffering from pregnancy malaria complications. Mechanisms responsible for increased susceptibility to malaria in pregnant ...
TRP-1 AS A MODEL TUMOR ANTIGEN FOR IMMUNOTHERAPY AND IMMUNE TOLERANCE IN THE THYMUS
immune tolerance T cells mTECs
2015/5/21
Tolerance mechanisms, which collectively work to prevent autoimmunity, play a key role in suppressing the adaptive immune response to tumor antigens. This phenomenon is attributed to the extensive ove...
Immune cells use 'bungee of death' to kill dangerous cells
Immune cells bungee of death dangerous cells
2010/3/10
Immune cells use a bungee-like nanotube to snare dangerous cells, according to new research funded by the Medical Research Council (MRC).The findings by researchers from Imperial College London show t...