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In Down syndrome cells, genome-wide disruptions mimic a senescence-like state（图）
唐氏综合症 细胞生物学 全基因组 破坏模仿 衰老样状态
2023/6/6
In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disr...
MONITORING OF AGRICULTURAL DROUGHT USING FORTNIGHTLY VARIATION OF VEGETATION CONDITION INDEX (VCI) FOR THE STATE OF TAMIL NADU, INDIA
Agricultural drought monitoring Vegetation condition index (VCI) Drought severity map Geographic Information Systems (GIS) Normalized differenced vegetation index (NDVI)
2018/11/9
India being an agrarian nation widely depends upon rainfall for its agricultural productivity. The failure of rainfall and hence shortfall of productivity badly affects national economy. With an intri...
Kent State Research Group Publishes Analysis of Primate Brains in Top Science Journal
Kent State Research Group Primate Brains Top Science Journal
2017/12/19
How different are human brains compared to the brains of other primates such as chimpanzees, gorillas and monkeys? It’s one of many important questions that scientists have asked for years while pursu...
Kent State Researchers Help Find Pathologic Hallmarks of Alzheimer’s Disease in Aged Chimpanzee Brains（图）
Kent State Researchers Pathologic Hallmarks Alzheimer’s Disease Aged Chimpanzee Brains
2017/9/1
Dementia affects one-third of all people older than 65 years in the United States. The most common cause of dementia is Alzheimer’s disease, a progressive, irreversible brain disease that results in i...
Georgia State Neuroscientists Rewire Brain Of One Species To Have Connectivity Of Another
Georgia State Neuroscientists Rewire Brain One Species Connectivity Of Another
2017/7/21
ATLANTA–Scientists at Georgia State University have rewired the neural circuit of one species and given it the connections of another species to test a hypothesis about the evolution of neural circuit...
Kent State University at Stark research unravels mysteries of mouthparts of butterflies
Kent State University Stark mouthparts butterflies
2017/4/27
Imagine that the way flies and butterflies drink nectar and other fluids can be imitated for use in medicine, potentially to deliver life-saving drugs to the body – and also how this method can save t...
Portland State research shows some viruses can infect even after major mutations
Portland State research some viruses infect
2017/3/30
Portland State University researchers have found that only about half the genes in a specific virus affecting single cell organisms is needed to infect a host. This means the virus can undergo major m...
Ground-state Proton Transfer Kinetics in Green Fluorescent Protein (GFP)
Mitotic centromere-associated kinase (MCAK/Kif2C) Cellular senescence p53 Human primary cells
2016/5/25
Proton transfer plays an important role in the optical properties of green fluorescent protein (GFP). While much is known about excited-state proton transfer reactions (ESPT) in GFP occurring on ultra...
Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D.2.Unusual Photophysical Properties
Arabidopsis thaliana homogentisate phytyltransferase (HPT/VTE2) Lactuca sativa tocopherol tocopherol cyclase (TC/VTE1) vitamin e
2016/5/25
In the preceding accompanying paper [Shu, X., et al. (2007) Biochemistry 46, 12005-12013], the 1.5 A resolution crystal structure of green fluorescent protein (GFP) variant S65T/H148D is presented, an...
Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D.1.Mutagenesis and Structural Studies
Arabidopsis thaliana homogentisate phytyltransferase (HPT/VTE2) Lactuca sativa tocopherol tocopherol cyclase (TC/VTE1) vitamin e.
2016/5/24
Wild type green fluorescent protein (wt-GFP) and the variant S65T/H148D each exhibit two absorption bands, A and B, which are associated with the protonated and deprotonated chromophores, respectively...
Green Fluorescent Protein Variants as Ratiometric Dual Emission pH Sensors.2.Excited-State Dynamics
Animals Protons Deuterium Luminescent Proteins Green Fluorescent Proteins Spectrometry, Fluorescence Biosensing Techniques Kinetics Genetic Variation Hydrogen-Ion Concentration
2016/5/24
In the preceding paper [Hanson, G. T., McAnaney, T. B., Park, E. S., Rendell, M. E. P., Yarbrough, D. K., Chu, S., Xi, L., Boxer, S. G., Montrose, M. H., and Remington, S. J. (2002) Biochemistry 41, 1...
Excited State Energy Transfer Pathways in Photosynthetic Reaction Centers.4.Asymmetric Energy Transfer in the Heterodimer Mutant
in-modified beta zeolite reductive solid-state ion exchange Lewis acidity m-xylene transformation
2016/5/23
In bacterial photosynthetic reaction centers, ultrafast singlet excited state energy transfer occurs from the monomeric bacteriochlorophylls, B, and bacteriopheophytins, H, to the homodimer special pa...
Excited State Electronic Asymmetry of the Special Pair in Photosynthetic Reaction Center Mutants:Absorption and Stark Spectroscopy
Dimerization Electron Transport Electrons Hydrogen Bonding Models, Chemical Mutagenesis, Site-Directed Oxidation-Reduction Photosynthetic Reaction Center Complex Proteins Rhodobacter sphaeroides Spectrophotometry Static Electricity
2016/5/23
The electronic absorption line shape and Stark spectrum of the lowest energy Q(y)() transition of the special pair in bacterial reaction centers contain a wealth of information on mixing with charge t...
Ultra-fast Excited State Dynamics in Green Fluorescent Protein:Multiple States and Proton Transfer
Protons Luminescent Proteins Green Fluorescent Proteins Recombinant Proteins Spectrometry, Fluorescence Temperature Amino Acid Sequence Protein Conformation Structure-Activity Relationship Oxidation-Reduction
2016/5/23
The green fluorescent protein (GFP) of the jellyfish Aequorea Victoria has attracted widespread interest since the discovery that its chromophore is generated by the autocatalytic, posttranslational c...
Excited State Energy Transfer Pathways in Photosynthetic Reaction Centers.1.Structural Symmetry Effects
biology and medicine,basic studies chemistry solar energy photosynthetic reaction centers energy transfer temperature dependence chemical reaction kinetics excited states molecular structure symmetry
2016/5/23
Ultrafast excited state energy transfer to the primary electron donor or special pair in photosynthetic reaction centers has been measured following excitation of the lowest electronic state of the ot...