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2017 基因组不稳定性和DNA修复 Keystone Symposia(2017 Keystone Symposia on Genomic Instability and DNA Repair)
Genomic Instability DNA Repair
2017/3/7
The meeting will begin on Sunday, April 2 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 6 with a closing plenary session ...
Structural Changes That Drive Timed Promoter Release In Transcription Reciprocally Lead To Abortive Instability
Biological sciences Aminopurine Abortive cycling Kinetics P266l Rna polymerase Transition Abortive instability
2014/12/10
RNA polymerases carry out a process, which at times carries contradictory mechanistic requirements. During initiation, an RNA polymerase should be highly sequence specific, binding only to and initiat...
Scientists link ALS progression to increased protein instability(图)
ALS protein instability
2014/12/1
LA JOLLA, CA—October 13, 2014—A new study by scientists from The Scripps Research Institute (TSRI), Lawrence Berkeley National Laboratory (Berkeley Lab) and other institutions suggests a cause of amyo...
Cascades of genetic instability resulting from compromised break-induced replication
Comparative Genomic Hybridization Break-induced Replication Copy Number Variations Chromosomal Rearrangements Double-strand Break Repair Half Crossover Homologous Recombination Non-reciprocal Translocation Half crossover instability cascades DNA double-strand break DNA repair Genetic instabilities Array-CGH
2015/5/22
Break-induced replication (BIR) is a mechanism to repair double-strand breaks (DSBs) that possess only a single end that can find homology in the genome. This situation can result from the collapse of...
Dynamic instability of a growing adsorbed polymorphic filament
mechanochemistry protein polymorphism dynamic instability microtubule actin elastic filament
2011/8/18
Abstract: The intermittent transition between slow growth and rapid shrinkage in polymeric assemblies is termed dynamic instability, a feature observed in a variety of biochemically distinct assemblie...
Dynamical membrane curvature instability controlled by intermonolayer friction
Dynamical membrane curvature intermonolayer friction phospholipid membrane
2011/8/16
Abstract: We study a dynamical curvature instability caused by a local chemical modification of a phospholipid membrane. In our experiments, a basic solution is microinjected close to a giant unilamel...
Monodisperse domains by proteolytic control of the coarsening instability
Monodisperse domains proteolytic control the coarsening instability
2011/9/7
The coarsening instability typically disrupts steady-state cluster-size distributions. We show that degradation coupled to the cluster size, such as arising from biological proteolysis, leads to a nov...
结直肠腺瘤的微卫星不稳定状态与相关基因表达的研究Microsatellite Instability and Relative Gene Expressions in Sporadic and Familial Adenomatous Polyposis Adenomas
结肠直肠癌 腺瘤 免疫组织化学 微卫星不稳定性
2008/1/10
摘要 应用微切割-聚合酶链反应-单链长度多态性(PCR-SSLP)的方法,检测59例62个结直肠腺瘤,包括散发性腺瘤及家族性腺瘤性息肉病(FAP)腺瘤在BAT26等16个微卫星基因座在结直肠腺瘤标本的微卫星不稳定性(MSI)状态;并应用免疫组织化学SP法检测β-连接素(β-catenin)、TP53、BAX等的表达情况,初步探讨错配修复(MMR)基因在结直肠癌发生的早期即腺瘤阶段的作用及其意义。结...
期刊信息
篇名
Genomic instability of prawn white spot bacilliform virus (WSBV) and its association to virus virulence
语种
英文
撰写或编译
作者
Yongsheng Lan,Wei Lu,Xun Xu
第一作者单位
刊物名称
Virus Research
页面
90:269-274.2002...