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单核苷酸多态性及其在鸡QTL定位上的应用--Single Nucleotide Polymorphism and Its Use in Chicken QTL Mapping
鸡 单核苷酸多态性(SNP) 遗传标记 QTL定位 chicken single nucleotide polymorphism (SNP) genetic marker QTL mapping
2007/12/5
单核苷酸多态性是指DNA序列上的单个碱基变异,它具有分布广、多态信息含量大、易于检测和统计分析等优点,能较好用于基因图谱构建和数量性状QTL定位研究,被称为继RFLP和微卫星标记之后的第3代基因遗传标记。本文综述了单核苷酸多态性的性质及检测技术、利用候选基因SNP进行鸡QTL定位研究的现状,并对未来SNP的应用前景进行了展望。
Single nucleotide polymorphism (SN...
Evaluation of Cofactor Markers for Controlling Genetic Background Noise in QTL Mapping
Heritability Marker Spacing QTL Simulation
2016/4/13
In order to control the genetic background noise in QTL mapping, cofactor markers were incorporated in single marker analysis (SMACO) and interval mapping (CIM). A simulation was performed to see how ...