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Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain
Humans Escherichia coli Benzamides Quinolines Nitriles Aniline Compounds Piperazines Pyrimidines Thiazoles Recombinant Proteins
2016/5/25
Chronic myeloid leukemia (CML) is caused by the kinase activity of the BCR-Abl fusion protein. The Abl inhibitors imatinib, nilotinib and dasatinib are currently used to treat CML, but resistance to t...
Spectroscopic analysis of interaction between an EIT wave and a coronal upflow region
Spectroscopic analysis of interaction between an EIT wave and a coronal upflow region
2011/10/20
We report a spectroscopic analysis of an EIT wave event that occurred in active region 11081 on 2010 June 12 and was associated with an M2.0 class flare. The wave propagated near circularly. The south...
Massive Stars in Transition：Spectroscopic Analysis of HR Carinae
Massive Stars HR Carinae Spectroscopic Analysis
2009/6/15
Massive Stars in Transition：Spectroscopic Analysis of HR Carinae。