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Dermatophytosis is most frequently found in ruminants, in which non-pruritic periocular lesions are most typical, though generalised skin disease may develop. Accordingly, the infection causes major e...
Pancreatic neuroendocrine tumours are rare tumours that can either present with syndromes from excess hormonal production or from mass effect – from the primary or metastases. They vary widely in clin...
The objective of this study was to determine the influence of TNF-alpha gene polymorphism at position –824 A > G on TNF-alpha gene expression in BLV-positive animals with aleukaemic (AL) and persisten...
Hypoxia is a condition in which an area of the body or a tissue is deprived of sufficient supply of oxygen. The lack of nutrients in a hypoxic tissue generally causes apoptosis but some cells are able...
Giant cell tumours (GCTs) of bone have been described as the most challenging benign bone tumors. It is very unusual for GCT to occur in patients younger than 20 yrs or older than 55 years. GCT is see...
Neuroendocrine tumours have posed a challenge for the development of research and management strategies because of their rarity and heterogeneity, both from clinical and molecular perspectives. Classi...
Here, we describe a case of a wild female badger (a sow) with disseminated serous adenocarcinoma of the ovary which corresponds to a group of low grade serous carcinomas of the ovary in humans. Beside...
This study describes a case of a six-year-old female crossbreed dog that had a three months history of progressive right thoracic limb lameness. Palpation revealed muscle atrophy of the scapular and h...
Ectopic ACTH secretion is provoked by extra-pituitary tumours that secrete ACTH, constituting an infrequent type of Cushing Syndrome in the dog. Neuroendocrine tumours (NET) are characterised by the s...
In recent years, significant emphasis has been placed on combination chemotherapy in cancer using cytotoxic agents and plant derived-bioactive substances that are capable of selectively arresting cell...
A four-year-old cross-breed and neutered bitch weighing 24 kg, was presented with vaginal bleeding for one month and a vaginal mass identified two previously. An ovariohysterectomy operation was perfo...
Metastatic cancers are often resistant to conventional chemotherapy and radiotherapy, reflecting an unmet need for novel therapeutic approaches to inhibit metastasis. Growing evidence highlights the i...
Circulating tumour cells – often referred to as a ‘liquid biopsy’ for cancer – can be found in a large proportion of patients with breast cancer that has spread to other organs. Changes in circulating...
Recent advances in genomic technology, in particular gene expression profiling, may elucidate novel tumour markers or signatures that will predict how various tumours will behave and respond to vario...
This paper reviews the evaluation of malignancy and prognostic parameters used in gastrointestinal stromal tumours (GIST). Incorporated is a case report of a duodenal GIST treated at our institutio...

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