搜索结果: 1-15 共查到“spike”相关记录27条 . 查询时间(0.053 秒)
华南农业大学动物科学学院博士生张以农在Nature Communications发表论文揭示家蚕质型多角体病毒spike蛋白的三维结构（图）
家蚕 多角体 BmCPV病毒 spike蛋白
2022/3/31
2022年1月27日，动物科学学院博士生张以农在学术期刊Nature Communications上发表题为“Multiple conformations of trimeric spikes visualized on a non-enveloped virus”的研究论文（论文链接：https://www.nature.com/articles/s41467-022-28114-0）。该论文首...
Researchers have found that the extinction at the end of the Permian period coincided with a sudden spike and subsequent drop in the ocean's oxygen content.
Key Residues of the Receptor Binding Motif in the Spike Protein of SARS-CoV-2 That Interact With ACE2 and Neutralizing Antibodies
SARS-CoV-2 cross-neutralizing antibody receptor binding motif spike protein substitution mutation
2020/6/11
Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein binds the host receptor angiotens...
Inhibition of SARS-CoV-2 (Previously 2019-nCoV) Infection by a Highly Potent Pan-Coronavirus Fusion Inhibitor Targeting Its Spike Protein That Harbors a High Capacity to Mediate Membrane Fusion
Inhibition SARS-CoV-2 Pan-Coronavirus Fusion Inhibitor Targeting High Capacity Mediate Membrane Fusion
2020/6/12
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeuti...
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Fusion mechanism 2019-nCoV inhibitors targeting HR1 domain spike protein
2020/6/12
Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for th...
Neutralizing acidic forest soils boosts tree growth,causes spike in nitrogen export
Neutralizing acidic soils tree growth causes spike nitrogen export
2016/7/4
A legacy of acid rain has acidified forest soils throughout the northeastern US, lowering the growth rate of trees. In an attempt to mitigate this trend, in 1999 scientists added calcium to an experim...
Termination of ongoing spike-wave discharges investigated by cortico–thalamic network analyses
spike-wave discharges cortico–thalamic network analyses
2015/5/5
Purpose: While decades of research were devoted to study generation mechanisms of spontaneous spike and wave discharges (SWD), little attention has been paid to network mechanisms associated with the ...
Peri-ictal network dynamics of spike-wave discharges: Phase and spectral characteristics
Cortico-thalamo-cortical system Network interactions Pairwise-phase-consistency Time-frequency-analysis Epileptic precursor activity Reticular-thalamic-nucleus Posterior thalamus Somatosensory cortex Spike-wave discharges WAG/Rij rats
2015/4/24
Purpose: The brain is a highly interconnected neuronal assembly in which network analyses can greatly enlarge our knowledge on seizure generation. The cortico-thalamo-cortical network is the brain-net...
Dynamics of the Dirac-Born-Infeld spike soliton
Oscillation the horizon transverse scalar field model system the dynamic degree of freedom
2014/12/22
We compare oscillations of a fundamental string ending on a D3-brane in two different settings: (1) a test string radially threading the horizon of an extremal black D3-brane and (2) the spike s...
A Banded Spike Algorithm and Solver for Shared Memory Architectures
SPIKE banded OpenMP linear system scaling
2014/12/8
A new parallel solver based on SPIKE-TA algorithm has been developed using OpenMP API for solving diagonally-dominant banded linear systems on shared memory architectures. The results of the numerical...
Enhanced Capabilities of the Spike Algorithm and a New Spike-OpenMP Solver
Compute High Performance Compute Algorithms Parallelism Banded Linear System
2014/12/8
SPIKE is a parallel algorithm to solve block tridiagonal matrices. In this work, two useful improvements to the algorithm are proposed. A flexible threading strategy is developed, to overcome limitati...
Monitoring spike train synchrony
data analysis synchronization spike trains clustering SPIKE-distance
2012/11/26
Recently, the SPIKE-distance has been proposed as a parameter-free and time-scale independent measure of spike train synchrony. This measure is time-resolved since it relies on instantaneous estimates...
Towards a learning-theoretic analysis of spike-timing dependent plasticity
dependent plasticity learning-theoretic analysis spike-timing
2012/11/26
This paper suggests a learning-theoretic perspective on how synaptic plasticity benefits global brain functioning. We introduce a model, the selectron, that (i) arises as the fast time constant limit ...
A Simple Probabilistic and Point-process Response Model for Predicting Every Spike in Optogenetics
optogenetics point processes generalized linear models response functions neuronal data generalized additive models prediction.
2012/9/19
Optogenetics is a new tool to stimulate genetically targeted neuronal circuits us-ing light flashes that can be delivered at high frequencies. It has shown promise for studying neural circuits that ar...