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山东大学医学院医学遗传学课件（七年制） polygenic inheritance。
Polygenic Resistance In The Highly DDT-resistant 91-R Strain Of Drosophila Melanogaster Involves Decreased Penetration, Increased Metabolism And Direct Excretion Of DDT
Resistance Metabolism P-glycoprotein
2014/10/21
Resistance to dichlorodiphenyltrichloroethane (DDT) in the 91-R strain of Drosophila melanogaster is extremely high compared to the susceptible Canton-S strain (>1500 times). Oxidative detoxification ...
Polygenic Modeling with Bayesian Sparse Linear Mixed Models
Polygenic Modeling Bayesian Sparse Linear Mixed Models
2012/11/23
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches ...
Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease
Integrated analysis of variants pathways genome-wide association studies polygenic models of disease
2012/9/18
Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on suscep-tibility to disease. These small effects are difficult to map reliably in genetic as...
The statistical mechanics of a polygenic characterunder stabilizing selection, mutation and drift
statistical mechanics polygenic characterunder stabilizing selection mutation drift
2010/11/15
By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation, and genetic drift. This requires us ...
RADIATION INDUCED POLYGENIC MUTATIONS IN SORGHUM BICOLOR L.
Sorghum bicolor irradiation induced mutation agronomic characters Pakistan
2009/9/29
A study was conducted in Department of Plant Breeding and Genetics, Sindh
Agriculture University, Tandojam, Pakistan. M1 population of two varieties (DS-
75 and Giza-3) of sorghum (Sorghum bicolor L...
Mechanism-as-activity and the threat of polygenic effects
causation mechanism Machamer activities explanation
2008/4/1
Polygenic effects have more than one cause. They testify to the fact that several causal contributors are sometimes simultaneously involved in causation. The importance of polygenic causation was noti...
14种多基因、疑为多基因遗传病的遗传率研究Estimation of heritability of 14 Kinds of Polygenic diseases
多基因遗传病 遗传率
2008/1/20
摘要0.75）; 共转性内斜视、唇裂±腭裂、先天性髋关节关节脱位、多指（趾）症、腹股沟斜疝、银屑病（牛皮癣）及原发性癫痫有遗传倾向（0.60< h2<0.75）； 而共转性外斜视、精索静脉曲张、隐睾症以及先天性心脏病（各型）受遗传因素的作用相对较小（h20.75). The congenital of genetic factors is moderate in con.comitant esot...
Mechanism-as-activity and the threat of polygenic effects
causation mechanism Machamer activities explanation
2011/9/7
Polygenic effects have more than one cause. They testify to the fact that several causal contributors are sometimes simultaneously involved in causation. The importance of polygenic causation was noti...