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Spontaneous micronuclei in cytokinesis-blocked bone marrow and peripheral blood Iymphocytes of CML patients
Micronucleus assay cytochalasine B bone marrow CML
2009/7/2
Some genetic diseases may have increased cellular instability. Since chronic myloid leukemia (CML) has a genetic base, we aimed to seek the genetic instability of patients by micronucleus analysis, a ...
Evaluation of Ribavirin Genotoxicity with Sister Chromatid Exchange and Micronuclei Assays in Humans
Ribavirin genotoxic effect sister chromatid exchange micronuclei formation
2009/5/20
Aim: The main objective of this study was to assess the genotoxicity of ribavirin in 15 patients who were suffering from Crimean-Congo haemorrhagic fever and treated with the therapy dose of the ant...
Clinico-pathological correlation of micronuclei in oral squamous cell carcinoma by exfoliative cytology
Exfoliative cytology micronuclei oral squamous cell carcinoma
2008/10/22
Oral squamous cell carcinoma accounts for 90% to 95% of all oral malignancies. Though its diagnosis seldom presents difficulty, it is the cancer staging and histopathological grading that are importan...
两例事故受照者染色体畸变分析及生物剂量估算Biological Dose Assessment by the Analyses of Chromosomal Aberrations and CB Micronuclei in Two Victims Accidentally Exposed to 60Co γ-rays
事故照射 染色体畸变 CB微核 生物剂量
2007/12/29
应用外周血淋巴细胞染色体畸变和CB微核分析方法,对2000年河南许昌“3.06”60Co辐射事故1例受照者(A)和2000年河南开封“6.26”辐射事故一例过量放射性核素内污染致γ射线照射受照者(B)的生物剂量进行估算。结果表明,“A”和“B”两例受照者依据双+环率估算的剂量分别为1.44Gy和0.15Gy,CB微核率估算的剂量分别为1.43Gy和0.22Gy,与用物理方法估算的剂量比较接近,亦与...
THE INDUCTION OF MICRONUCLEI IN BOVINE LYMPHOCYTES BY EXPOSURE TO BENZENE AND S-9 MIX
benzene bovine peripheral lymphocytes frequency of micronuclei
2010/12/24
Benzene is a widespread human carcinogen, inducing leukaemia and hematotoxicity. It has been shown to be a multi-organ carcinogen in animals. The effect of benzene was studied using induction of micro...