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骨质疏松症一种以骨量低下、骨组织微结构损坏，导致骨脆性增加，易发生骨折为特征的全身性骨病。大量研究证实，细胞外囊泡（EVs）在调控骨稳态的复杂机制中发挥重要的作用，这些囊泡在病理和生理环境中都起着至关重要的作用，而不同来源的EVs对骨质疏松症有明显且不同的影响。
近日，华西基础医学与法医学院刘肖珩教授团队在Bone Research发表原创研究论文，证实了基质囊泡来源的AnxA5在骨重塑中的重要作用，阐明了AnxA5通过促进基质囊泡与I型胶原的黏附，诱导骨前体细胞发生自噬和加速矿化预防骨丢失的新机制，为骨质疏松症的防治提供新策略。
西北工业大学生命学院骞爱荣教授团队主编《BONE CELL BIOMECHANICS, MECHANOBIOLOGY, AND BONE DISEASES》在爱思唯尔（ELSEVIER）出版集团正式出版（图）
骞爱荣 爱思唯尔 生物力学 骨疾病 骨细胞
2024/4/3
近日，由西北工业大学生命学院骞爱荣教授和胡丽芳副教授主编的英文专著《BONE CELL BIOMECHANICS, MECHANOBIOLOGY, AND BONE DISEASES》（中文译名：骨细胞生物力学、力学生物学和骨疾病）在国际知名出版社爱思唯尔（ELSEVIER）正式出版。
RNA nanoparticle therapy stops the spread of incurable bone marrow cancer（图）
RNA 纳米颗粒疗法 骨髓癌 肿瘤治疗
2023/6/27
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
The strongest part of a tree lies not in its trunk or its sprawling roots, but in the walls of its microscopic cells.
A Cornell-led collaboration has been awarded a five-year, $3.6 million grant from the National Institutes of Health to explore the ways that the gut microbiome – that mass of microorganisms inside us ...
Facile synthesis of multifunctional bone biochar composites decorated with Fe/Mn oxide micro-nanoparticles: Physicochemical properties, heavy metals sorption behavior and mechanism
biochar composites Fe/Mn oxide micro-nanoparticles heavy metals sorption
2023/6/5
The value-added utilization of waste resources to synthesize functional materials is important to achieve the environmentally sustainable development. In this work, novel micro-nano FeOx- and MnOx-mod...
Micro-nano-engineered nitrogenous bone biochar developed with a ball-milling technique for high-efficiency removal of aquatic Cd(II), Cu(II) and Pb(II)
Micro-nano-engineered nitrogenous bone biochar
2023/6/5
A cost-effective and eco-friendly engineering method to improve biochar’s physicochemical and sorption performance is critical in various environmental applications. In this study, micro-nano-engineer...
CT Bone Reading软件对肋骨骨折\诊断效能的应用价值
肋骨骨折 计算机体层成像 多平面重建 容积再现
2020/10/15
评价CT Bone Reading软件对肋骨骨折诊断效能的影响。 方法 纳入101例经CT检查诊断为肋骨骨折的患者。所有CT数据分别行薄层重建（0.6 mm）和8 mm重建。分别由2名低年资放射科医生应用CT Bone Reading、CT trauma软件及8 mm重建图像对肋骨骨折进行双盲评估，并比较3种阅片方式的诊断准确性及阅片时间。
2019年2月13日—17日，一年一度的北美颅底外科协会（NASBS）年会在美国召开，重医附一院神经外科杨刚主任医师作为中国参会的五名代表之一受邀出席并发表演讲，由他首创并命名的“In Situ Bone Flap”（原位骨瓣）在内镜下扩大经鼻入路术后颅底重建方面的经验轰动全场。
首都医科大学王松灵教授团队《Bone Research》揭示miRNA通过外泌机制精准调控牙齿形态发育（图）
首都医科大学 王松灵 教授 Bone Research miRNA 外泌机制 精准调控 牙齿形态发育
2018/10/29
2018年9月，口腔医院/基础医学院王松灵教授团队在《Bone Research》(IF:9.051)上发表了题为"Mandible exosomal ssc-mir-133b regulates tooth development in miniature swine via endogenous apoptosis"的论文。文章阐释了在大型哺乳动物模型中，研究团队首次发现一个重要的功能性miR...
2018年5月24日，国际学术期刊Bone Research在线发表了中国科学院生物化学与细胞生物学研究所邹卫国研究组的综述文章“Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts”。该文章系统阐述了成骨细胞...
四川大学组织学与胚胎学英文课件 Bone and cartilage。
Bone mineral density during pregnancy in women participating in a randomized controlled trial of vitamin D supplementation
bone mineral content bone mineral density cholecalciferol pregnancy vitamin D
2018/11/21
Background: Little is known about bone mineral density (BMD) during pregnancy. Advances in technology with lower radiation emissions by dual-energy X-ray absorptiometry instruments now permit the safe...