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Mechanisms of binding diversity in protein disorder : molecular recognition features mediating protein interaction networks
Many-to-one binding Partner selection MoRF
2015/5/25
Intrinsically disordered proteins are proteins characterized by lack of stable tertiary structures under physiological conditions. Evidence shows that disordered proteins are not only highly involved ...
Protein Interaction Networks are Fragile against Random Attacks and Robust against Malicious Attacks
Protein Interaction Networks Fragile against Random Attacks Robust against Malicious Attacks
2010/11/16
The capacity to resist attacks from the environment is crucial to the survival of all organisms. We quantitatively analyze the susceptibility of protein interaction networks of numerous organisms to r...
The role of charged surface residues in the binding ability of small hubs in protein-protein interaction networks
protein-protein interaction networks hubs electrostatic potential multipole expansion surface charge
2010/12/2
Hubs are highly connected proteins in a protein-protein interaction network. Previous work has implicated disordered domains and high surface charge as the properties significant in the ability of hub...