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Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Structure Mpro SARS-CoV-2 discovery inhibitors
2020/6/12
A new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the aetiological agent responsible for the 2019–2020 viral pneumonia outbreak of coronavirus disease 2019 (...
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Fusion mechanism 2019-nCoV inhibitors targeting HR1 domain spike protein
2020/6/12
Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for th...
Effects of Histone Deacetylase Inhibitors on Vitamin D Activity in Human Breast Cancer Cells
Sulforaphane histone deacetylase inhibitors vitamin D receptor
2014/11/7
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
HISTONE DEACETYLASE INHIBITORS TRICHOSTATIN A (TSA) AND SULFORAPHANE (SFN) MODULATE VITAMIN D RESPONSIVE CYP24 GENE EXPRESSION in 3T3-L1 PREADIPOCYTES
TRICHOSTATIN A (TSA) SULFORAPHANE (SFN), CYP24 3T3-L1 PREADIPOCYTES
2014/11/7
Vitamin D plays an important role in preserving healthy bones, and has additional roles in the body, including modulation of cell growth, differentiation, neuromuscular and immune function, and anti-i...
Selective Serotonin Reuptake Inhibitors and Bone Mineral Density in a Population of U. S. Premenopausal Women
Selective Serotonin Reuptake Inhibitors Bone Mineral Density Bone Mineral Content Dual Energy X-ray Absorptiometry Premenopausal
2014/11/6
Low bone mineral density (BMD) in post-menopausal women is a risk factor for bone fractures and osteoporosis development. Prior studies in post-menopausal women have shown the use of antidepressant me...
期刊信息
篇名
(2)α,α-Trehalose derivatives bearing guanidine groups as inhibitors to HIV-1 Tat-TAR RNA interaction in human cells.
语种
英文
撰写或编译
作者
王敏,杨铭
第一作者单位
刊物名称
Bioorganic & Medicinal Chemistry Letters
页...
Relation of Factor VIII and IX Inhibitors with ABO Blood Groups in 150 Patients with Haemophilia A and B
ABO Blood Groups Factor VIII and Factor IX inhibitor Haemophilia
2010/2/5
Many investigations have proved relations between ABO blood groups with some diseases and factor VIII and von willebrand level in plasma. In this study we investigated a relation between ABO blood gro...
Soy sterol esters and b-sitostanol ester as inhibitors of cholesterol absorption in human small bowel
Plant sterols phytosterols plant sterol ester, cholesterol absorptionson
2016/6/3
Background: Plant sterols are natural dietary components with
serum cholesterol–lowering properties. The lowering of serum
cholesterol by plant sterols is believed to be the result of an inhibition
...