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Researchers from Harvard’s Stem Cell and Regenerative Biology (HSCRB)’s Zon lab have discovered a new mechanism that influences melanoma development, a finding that could have wide implications for pa...
Malignant Melanoma of Nose and Paranasal Sinuses: 2 Case Reports
Malignant Melanoma Nose Paranasal sinuses
2015/7/16
Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs ...
Melanoma
Melanoma natural history
2015/4/8
Forty years ago the causes, incidence and natural history of melanoma were still poorly understood. Little was known
about prognostic factors, and radical surgery was routine for all melanomas. Howe...
This review discusses the relevant imaging techniques for both melanoma and non-melanoma skin cancers, including
basal cell carcinomas, cutaneous squamous cell carcinomas and Merkel cell carcinomas....
Recent advances and important issues in melanoma pathology: an update for oncologists
melanoma pathology Recent advances
2015/4/7
The critical role of pathology in the multidisciplinary care of melanoma patients is becoming apparent in the
rapidly changing modern era of personalised and precisely targeted medicine. Recent insi...
New systemic therapies for metastatic melanoma – mapk inhibitors and immunotherapy
metastatic melanoma mapk inhibitors
2015/4/7
Metastatic melanoma has a poor prognosis and until recently systemic therapy was ineffective. Advances in the
understanding of tumour biology and immune regulation have led to the development of tar...
Melanoma: narrowing the sights on an evasive enemy
Melanoma narrowing the sights an evasive enemy
2015/3/23
Much of the resistance of melanoma to immunotherapy, radiotherapy and cytotoxic treatment is due to an impressive array of molecular defences that derive ultimately from the essential molecular struct...
The surgical management of cutaneous melanoma: have we made any real progress in 100 years?
The surgical management cutaneous melanoma 100 years
2015/3/23
In the early 20th Century, excision of all primary melanomas with >5cm clearance margins was recommended, with amputation in selected cases – recommendations based on experience of a few patients with...
ADVANCED NON-MELANOMA SKIN CANCERS OF THE HEAD AND NECK: AN OVERVIEW ON MANAGEMENT
MANAGEMENT Skin cancer
2015/3/20
Non-melanoma skin cancers occur at an epidemic rate in Australia and are increasing in incidence worldwide. In most
patients local treatment is curative. However, a subset of patients will be diagnos...
This edition of Cancer Forum reports a series of papers prepared for a Festschrift held in honour of
Emeritus Professor William McCarthy AM at the Royal Prince Alfred Hospital on 29 July 2005. Profes...
Routine skin examination, either conducted by a doctor or by self-screening, is widely practised in Australia, although
authoritative groups and clinical guidelines do not recommend screening. This i...
Two relatively new methods have changed the way primary melanoma is diagnosed. Dermoscopy (surface microscopy,
epiluminescence microscopy) is a technique that was introduced at the beginning of the 1...
Magnetic resonance spectroscopy in the management of melanoma
melanoma Magnetic resonance spectroscopy
2015/3/18
The surgical treatment of melanoma has been progressively rationalised during the last two decades. Radical excision of primary
tumours and elective (prophylactic) resection of regional lymph nodes h...
GENETIC RISK AND MELANOMA
MELANOMA GENETIC RISK
2015/3/18
This paper reviews current understanding of the role of genetic factors in the causation of melanoma. Three genes have a proven
role in influencing melanoma susceptibility: CDKN2A (p16INK4A) and its ...
Collaboration between clinicians and pathologists: a necessity for the optimal management of melanoma patients
clinicians pathologists
2015/3/18
Pathological assessment of a tissue biopsy is a critical aspect in the multidisciplinary management of melanoma patients because
it not only establishes a definite diagnosis in most cases but also pr...