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Androgen regulation of the human ornithine decarboxylase promoter in prostate cancer cells
Androgen receptor gene regulation
2009/2/17
We studied the response of the human ornithine decarboxylase (ODC) promoter to androgen in human prostate cancer cell lines. In the well-differentiated, androgen-sensitive human prostate cancer li...
Analysis of promoter and androgen regulatory sequences required for optimal transcription of the rat androgen-binding protein gene
Androgen-binding protein (ABP) sex hormone-binding globulin (SHBG) Sertoli cells transcriptional regulation
2009/2/17
The androgen-binding protein (ABP) gene P1 promoter directs cell-specific gene regulation of ABP secreted by Sertoli cells. A recent study using the mouse Sertoli cell line (MSC-1) with a luciferase...
Search for androgen response elements in the proximal promoter of the canine prostate arginine esterase gene
Androgenic regulation kallikreins prostate-specific antigen androgen receptor binding
2009/2/13
We have demonstrated the binding of the recombinant DNA binding domain of the rat androgen receptor to a DNA sequence of the canine prostate arginine esterase gene and have determined the functio...
E2F and GATA-1 are required for the Sertoli cell-specific promoter activity of the follicle-stimulating hormone receptor gene
Transcription factor testis gonadotropin
2008/12/29
The follicle-stimulating hormone receptor (FSHR) gene is expressed in Sertoli cells in males and in granulosa cells in females. Cis-acting sequences and associated binding factors responsible for ...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Recapitulation of Germ Cell- and Pituitary-Specific Expression With 1.6 kb of the Cystatin-Related Epididymal Spermatogenic（Cres）Gene Promoter in Transgenic Mice
Epididymis testis spermatogenesis gene regulation
2008/12/23
The Cres (cystatin-related epididymal spermatogenic) gene encodes the defining member of a new subgroup within the family 2 cystatins of cysteine protease inhibitors. Cres expression is highly tis...
Construction of Prostate-Specific Expressed Recombinant Plasmids With High Transcriptional Activity of Prostate-Specific Membrane Antigen（PSMA）Promoter/Enhancer
Adenocarcinoma regulatory element
2008/12/23
To screen different combinations of prostate-specific membrane antigen (PSMA) promoter/enhancer with the strongest transcriptional activity in prostate-specific cells, we used PSMA regulatory elemen...
A Transgenic Analysis of Mouse Lactate Dehydrogenase c Promoter Activity in the Testis
Transcription mRNA stability protein stability
2008/12/19
Transcription of the mouse testis-specific lactate dehydrogenase c (mldhc) gene is limited to cells of the germinal epithelium. Cloning and analysis of the mldhc promoter revealed that a 100-bp co...