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Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate
GnRH agonist LH testosterone testis morphology electron microscopy monkeys
2009/2/23
The present investigation evaluates the long-term effects of GnRH agonist treatment on testicular histology, sperm production and the subsequent recovery of these parameters. Four adult rhesus monke...
Stimulation of sperm production by human chorionic gonadotropin after prolonged gonadotropin suppression in normal men
sperm production human chorionic gonadotropin prolonged gonadotropin suppression normal men
2009/2/20
The precise hormonal milieu required for quantitatively normal spermatogenesis in man is unclear. The authors previously have shown that both supraphysiologic dosages of human chorionic gonadotropin...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Potential daily sperm production, Sertoli cell number, and seminiferous tubule characteristics in beef bulls fed conventional or gossypol-enriched diets
Potential daily sperm production Sertoli cell number seminiferous tubule characteristics
2009/2/18
The objective of this study was to determine the amount of germ cell degeneration throughout spermatogenesis in the bull and to determine if gossypol-enriched diets enhance that degeneration. Twenty...
Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse
Testis propylthiouracil Sertoli cells hypothyroidism
2009/2/12
Male rats made hypothyroid during neonatal life show unprecedented increases in adult testis size and daily sperm production (DSP). To determine if this effect was unique to the rat or could also ...
Leydig cell cytoplasmic content is related to daily sperm production in men
Leydig cell smooth endoplasmic reticulum
2009/2/6
The relationship between the abundance of specific Leydig cell organelles and daily sperm production (DSP) was determined. Testes from 10 men (26-53 years of age) were obtained at autopsy within 10 ...
Reducing Estrogen Synthesis in Developing Boars Increases Testis Size and Total Sperm Production
Aromatase inhibition Sertoli cell Leydig cell
2008/12/24
The abundant production of testicular estrogens and the presence of both ESR1 and ESR2 within boar testes are consistent with a role for estrogen in testicular development and/or function in this sp...
Intratesticular Testosterone Concentrations Comparable With Serum Levels Are Not Sufficient to Maintain Normal Sperm Production in Men Receiving a Hormonal Contraceptive Regimen
Intratesticular androgens spermatogenesis gonadotropins progestogens
2008/12/22
Intratesticular testosterone (ITT) is thought to play a key role in the control of spermatogenesis in man but is rarely measured. The purposes of this study were 1) to examine the relationship betwe...