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Heterogeneity of sperm density profiles following 16-week therapy with continuous infusion of high-dose LHRH analog plus testosterone
sperm density profiles 16-week therapy high-dose LHRH testosterone
2009/2/23
LHRH agonist analogs have been investigated as potential male contraceptives. It has been shown that the LHRH agonistic analog [D-Trp6,Pro9-NEt] LHRH (LHRHA) given to men in single doses up to 500 m...
Heterogeneity of sperm density profiles following 20-week therapy with high-dose LHRH analog plus testosterone
LHRH analog sperm density heterogeneous response
2009/2/20
Eight normal male volunteers received an LHRH analog, 100 to 500 micrograms daily, for 20 weeks. Testosterone enanthate, 100 mg, was given by injection every second week. Sperm density fell to 5.5 X...
Individual differences in LH and FSH responses to orchidectomy and testosterone replacement therapy in rams
Individual differences LH FSH rams
2009/2/19
Profiles of LH and FSH levels and pituitary LH responses to exogenous luteinizing hormone releasing hormone (LHRH) have been characterized in rams, castrated rams (wethers), and wethers implanted wi...
The effect of follicle-stimulating hormone therapy on sperm quality：an ultrastructural mathematical evaluation
follicle-stimulating hormone therapy sperm quality ultrastructural mathematical evaluation
2009/2/17
We investigated the effect of follicle-stimulating hormone (FSH) administration on the ultrastructure of spermatozoa in order to evaluate the potential of FSH therapy for improving sperm quality. Fo...
Changes in the hypothalamic-pituitary-gonadal axis in men after cadaver kidney transplantation and cyclosporine therapy
Renal transplantation hormonal changes androgens estrogen
2009/2/11
A variety of plasma androgens, estradiol, follicle-stimulating hormone, luteinizing hormone, prolactin, cortisol, and thyroid parameters were examined in 10 men followed serially before and after ...
The emerging role of alpha antagonists in the therapy of benign prostatic hyperplasia
Benign prostatic hyperplasia alpha blockade
2009/2/7
The rationale for using alpha blockade to treat benign prostatic hyperplasia (BPH) is based on the physiology and pharmacology of prostate smooth muscle. Approximately 20% of the area density of the...
In vitro fertilization with intracytoplasmic sperm injection is an effective therapy for male factor infertility related to subnormal hypo-osmotic swelling test scores
vitro fertilization sperm injection male factor infertility
2008/12/26
The aim of the study was to determine if intracytoplasmic sperm injection (ICSI) would be an effective therapy for mates with subnormal hypo-osmotic swelling test (HOST) scores, a condition known to...
Peyronie's disease：etiology, medical, and surgical therapy
Peyronie's disease etiology medical surgical therapy
2008/12/25
Peyronie's disease remains an enigma. With the recent introduction of an animal model for Peyronie's disease, the entry of a number of double-blind placebo-controlled clinical trials, and the applic...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Circulating Inflammatory Cytokine Expression in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Hypogonadism inflammation
2008/12/24
Prostate cancer (PCa) is one of the most common cancers in men. Androgen deprivation therapy (ADT) is employed in the treatment of patients with metastatic or recurrent PCa, resulting in castrate le...
Testosterone Replacement Therapy for Male Aging：ASA Position Statement
Testosterone Replacement Therapy Male Aging ASA Position Statement
2008/12/23
The American Society of Andrology suggests that testosterone replacement therapy in aging men is indicated when both clinical symptoms and signs suggestive of androgen deficiency and decreased testo...
Testosterone Replacement Therapy for Older Men
Testosterone Replacement Therapy Older Men
2008/12/23
The interest in possible medical interventions to promote healthy aging has been recently increasing, as the absolute number and the proportion of men over 60 years of age is expected to increase duri...
Combination Therapy: Medicated Urethral System for Erection Enhances Sexual Satisfaction in Sildenafil Citrate Failure Following Nerve-Sparing Radical Prostatectomy
Erectile dysfunction MUSE intraurethral alprostadil
2008/12/23
The objective of our study was to assess the effectiveness of combining medicated urethral system for erection (MUSE) with sildenafil citrate in men unsatisfied with the sildenafil alone. Baseline a...
Gonadotropin-Releasing Hormone Antagonist (Cetrorelix) Therapy Fails to Protect Nonhuman Primates（Macaca arctoides）From Radiation-Induced Spermatogenic Failure
Macaque testis spermatogenesis
2008/12/23
Treatment of men of reproductive age with radiation or alkylating agents often produces prolonged azoospermia. We previously demonstrated that suppression of testosterone (T) with gonadotropin-rel...
Oxidative Stress and Antioxidant Therapy：Their Impact in Diabetes-Associated Erectile Dysfunction
Impotence vitamin E sildenafil nitric oxide phosphodiesterase type
2008/12/22
Oxidative stress is believed to affect the development of diabetic-associated vasculopathy, endothelial dysfunction, and neuropathy within erectile tissue. Our hypothesis is that, given adequate con...