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Comparison of Lactate Threshold, Glucose, and Insulin Levels Between OLETF and LETO Rats After All-Out Exercise
NIDDM OLETF treadmill running all-out exercise lactate velocity of lactate threshold
2015/4/23
Otsuka Long-Evans Tokushima Fatty (OLETF) rats are an animal model for obesity and Non Insulin Dependent Diabetes Mellitus by hyperphagia. The lactate threshold (LT) is used to determinate aerobic cap...
目的观察利拉鲁肽对糖耐量异常大鼠胰岛炎症因子白细胞介素-1β(IL-1β)和凋亡基因caspase3表达的影响。方法12周龄糖耐量异常OLETF大鼠分为生理盐水组和不同剂量利拉鲁肽干预组（50、100、200 μg/kg），8只LETO作为正常对照组。实验12周结束时，所有大鼠均检测糖耐量试验空腹及服糖后30 min胰岛素，并检测胰岛IL-1β和caspase3 mRNA和蛋白水平。结果利拉鲁肽干...