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2017 I型干扰素 Keystone Symposia（2017 Keystone Symposia on Type I Interferon: Friend and Foe Alike）
Immune Signal Nucleic Acids
2017/1/13
The meeting will begin on Sunday, March 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, March 23 with a closing plenary sessio...
The Association between Human Leukocyte Antigen Class II DR3–DQ2 Haplotype and Type 1 Diabetes in Children of the East Azerbaijan State of Iran
Haplotype Genotype HLA-DRB1 HLA-DQB1
2015/11/9
Background: Type 1 diabetes mellitus (T1D) is an autoimmune disease. Several associations between human leukocyte antigen (HLA) complex and T1D were found in various populations. Associations with var...
Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain
Tetanus Toxin Release Synaptosomes Transmitters Mechanisms
2015/7/15
This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomi...
Dissecting Neurofibromatosis Type 1 Related Vasculopathy
Neurofibromatosis type 1 suppressor gene
2015/5/25
Neurofibromatosis type 1 (NF1) is a genetic disorder resulting from mutations in the tumor suppressor gene NF1. NF1 encodes the protein neurofibromin, which functions to negatively regulate p21Ras sig...
Impairments in Local Heat Loss in Type 1 Diabetes during Exercise in the Heat
SWEATING SKIN BLOOD,FLOW CORE,TEMPERATURE THERMOSENSITIVITY CHRONIC,DISEASE
2017/5/25
Studies show that vasomotor and sudomotor activities are compromised in individuals with Type 1 diabetes mellitus (T1DM), which could lead to impaired skin blood flow (SkBF) and sweating during heat s...
Parathyroid Hormone Enhances Mechanically Induced Bone Formation, Possibly Involving L-Type Voltage- Sensitive Calcium Channels
parathyroid hormone bone formation
2014/12/4
PTH and mechanical loading might act synergistically on bone formation. We tested the in vivo effect of the L-type voltage-sensitive calcium channel (VSCC) blocker, verapamil, on bone formation induce...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM tension nanoscale
2014/12/4
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Effects of a Low-Volume Aerobic-Type Interval Exercise on V˙O2max and Cardiac Mass
Cardiac function cardiac magnetic resonance imaging exercise training maximal oxygen uptake myocardium
2017/5/17
The aim of this study was to compare the effects of time-efficient, low-volume interval exercises on cardiorespiratory capacity and left ventricular (LV) mass with traditional continuous exercise in s...
Botulinum Toxin Type A Therapy in Migraine:Preclinical and Clinical Trials
Botulinum Toxin Type A Nitroglycerin Randomized Controlled Trial
2015/10/9
Background: Botulinum toxin type A (BTX-A) has been reported to be effective for the therapy for migraine. The purpose of this study was to investigate the effect of BTX-A on the immunoreactive levels...
Association of Depression and Anxiety With Diabetes Mellitus Type 2 Concerning Some Sociological Factors
Depression Anxiety Diabetes Mellitus Type 2
2015/10/8
Background: Diabetes is a metabolic disorder with a high worldwide prevalence. It has been reported that diabetic patients are more prone to depression and anxiety.
Analyzing the Relationship Between Job Stress to Mental Health, Personality Type And Stressful Life Events of the Nurses Occupied in Tehran 115 Emergency
Mental Health Type A Personality Life Change Events Emergencies
2015/9/30
Nursing are known as a profession that is constantly exposed to various stresses. Stress job in this profession could lead to disturbances that seriously put at risk the mental health of nurses. Press...
Eccentric Exercise Increases Satellite Cell Content in Type II Muscle Fibers
MUSCLE STEM CELLS DLK PCNA
2017/7/14
Introduction: Satellite cells (SCs) are of key importance in skeletal muscle tissue growth, repair, and regeneration. A single bout of high-force eccentric exercise has been demonstrated to increase m...
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake
NMDA受体 NMDA D-AP-5 杏仁中央核 食物摄取 水摄取
2012/6/28
目的探讨杏仁中央核中的N-甲基-D-天冬氨酸（NMDA）型谷氨酸受体对食物和水摄取的影响。方法不锈钢套管植入雄性Sprague-Dawley大鼠一侧杏仁中央核内，NMDA型谷氨酸受体激动剂原型物NMDA，或选择性NMDA受体拮抗剂D(?)-2-氨基-5-磷酰基戊酸（D-AP-5）微量注射入饱食和含水度正常的大鼠的杏仁中央核内。结果杏仁中央核内注射入8.50，17.00，或34.00 nmol NM...
Effects of kirenol on bovine type II collagen-induced rat lymphocytes in vivo and in vitro
奇壬醇 II型胶原 淋巴细胞 类风湿性关节炎
2012/4/24
目的观察奇壬醇对牛II 型胶原特异性淋巴细胞体内和体外的免疫调节作用，探讨奇壬醇对抗原特异性淋巴细胞的免疫抑制作用机制。方法将Wistar 大鼠随机分为对照组、模型组、奇壬醇组和泼尼松龙组。除对照组外，均复制胶原诱导关节炎大鼠模型，造模当天开始给药。造模30 d 后取脾脏和引流淋巴结，制备单细胞悬液，经体外培养48 h 后，ELISA法检测培养上清中干扰素-γ（IFN-γ）、白介素-10（IL-1...
Levels of Haemophilus influenzae type B (Hib) antibody in Turkey before routine immunization
Haemophilus influenzae type b antibody serosurveillance
2010/12/21
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introductio...