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An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation
Ref-1 DNA-binding activity signaling
2014/12/12
The Ref-1 (also called APE or HAP1) protein is a bifunctional enzyme impacting on a wide variety of important cellular functions. It acts as a major member of the DNA base excision repair pathway. Mor...
The Fatty Acid Amide Hydrolase in Lymphocytes from Sedentary and Active Subjects
ENDOCANNABINOIDS ENERGYHOMEOSTASIS INFLAMMATION INTERLEUKIN6 LIFESTYLE PHYSICALEXERCISE
2017/5/17
Endocannabinoids (eCB) and interleukin 6 (IL-6) levels change during physical activity, thus suggesting their involvement in the modulation of exercise-related processes like inflammation and energy h...
Effects of kirenol on bovine type II collagen-induced rat lymphocytes in vivo and in vitro
奇壬醇 II型胶原 淋巴细胞 类风湿性关节炎
2012/4/24
目的观察奇壬醇对牛II 型胶原特异性淋巴细胞体内和体外的免疫调节作用，探讨奇壬醇对抗原特异性淋巴细胞的免疫抑制作用机制。方法将Wistar 大鼠随机分为对照组、模型组、奇壬醇组和泼尼松龙组。除对照组外，均复制胶原诱导关节炎大鼠模型，造模当天开始给药。造模30 d 后取脾脏和引流淋巴结，制备单细胞悬液，经体外培养48 h 后，ELISA法检测培养上清中干扰素-γ（IFN-γ）、白介素-10（IL-1...
A Study of T and B Lymphocytes and NK Cells in Healthy and Preeclamptic Pregnant Women
Preeclampsia T Iymphocytes B Iympocytes NK cells
2009/7/3
There are various theories concerning the etiology of preeclampsia and eclampsia. According to one of these, the immunologic mechanism may play a role. The aim of this study was to determine whether o...
Chromosomal Aberrations in Peripheral Lymphocytes of a High-Voltage Power Lineman Exposed to Electromagnetic Fields
Chromosomal aberrations Human peripheral lymphocytes Electromagnetic fields
2009/7/2
During the last decade, several studies have focused on the adverse effects on health caused by exposure to electromagnetic fields (EMF). Some epidemiological studies of workers exposed to EMF have sh...
CONTACT ALLERGY TO NICKEL: PATCH TEST SCORE CORRELATES WITH IL-5, BUT NOT WITH IFN-GAMMA NICKEL-SPECIFIC SECRETION BY PERIPHERAL BLOOD LYMPHOCYTES
allergic contact dermatitis patch test contact allergy lymphocytes
2010/12/22
Traditionally, allergic contact dermatitis (ACD) has been associated with the activity of Th1 lymphocytes that secrete interferon gamma. Recent evidence indicates that other cells.
A Preliminary Study of DNA Damage in Peripheral Lymphocytes from Lung Cancer Patients and Healthy Subjects
Comet assay DNA damage Lung cancer Lymphocyte
2009/6/24
A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung ca...
Sister Chromatid Exchange Frequency in Lymphocytes Cultured from Cotton Gin Workers
genotoxicity SCE mutagen cotton dust occupational exposure
2009/6/23
Genetic biomonitoring of human populations exposed to potential mutagens/carcinogens can be performed using different genetic markers. Sister chromatid exchange (SCE) is one of the most extensively us...
Genotoxic Evaluation of the Antibacterial Drug,Ciprofloxacin,in Cultured Lymphocytes of Patients with Urinary Tract Infection
Ciprofloxacin sister chromatid exchange mitotic index replicative index
2009/6/23
Ciprofloxacin is a quinolone carboxylic acid derivative and is commonly used in medicine. The genotoxicity of ciprofloxacin was evaluated in cultured human peripheral blood lymphocytes in patients wit...
The Effect of Glutathione S-transferase M1 Genotype on Benzo[a]pyrene-Induced Sister Chromatid Exchanges and Chromosomal Aberrations in Peripheral Blood Lymphocytes
Department of Medical Biology,Cerrahpaş a Faculty of Medicine,University of İ stanbul,İ stanbul-Turkey
2009/6/23
Sister chromatid exchange (SCE) and chromosomal aberration (CA) in peripheral lymphocytes have been widely used in assessing exposure to mutagens and carcinogens. One of the extensively studied genoto...
FISH DETECTION OF CHROMOSOME 1 ABERRATION IN HUMAN INTERPHASE AND METAPHASE LYMPHOCYTES AFTER EXPOSURE TO BENZENE
benzene occupational contaminant human lymphocytes chromosome 1
2010/12/23
Benzene is a relatively common environmental and occupational contaminant with carcinogenic and clastogenic properties. Therefore, further understanding of the adverse effect of benzene is still a mat...
EXPRESSION OF CELLULAR ISOFORM OF PRION PROTEIN ON THE SURFACE OF PERIPHERAL BLOOD LYMPHOCYTES AMONG WOMEN EXPOSED TO LOW DOSES OF IONIZING RADIATION
radiation exposure cellular isoform of prion lymphocytes
2010/12/23
Ionizing radiation affects the expression of adhesive and co-stimulatory molecules in lymphocytes. The physiological function of cellular isoform of prion protein (PrPc) is little known.
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AFP triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of lympho...
CD40 Ligand Expression on Stimulated T-Helper Lymphocytes in Patients with Common Variable Immunodeficiency
Common Variable Immunodeficiency (CVID) CD40 Ligand (CD154)
2010/4/20
Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency, characterized by reduced serum immunoglobulins levels and increased susceptibility to recurrent pyog...
Flow cytometric analysis of lymphocytes and lymphocyte subpopulations in induced sputum from patients with asthma
bronchial asthma CD4-positive lymphocyte flow cytometry induced sputum interleukin-2 receptor
2010/11/25
Study objectives were to compare the numbers of lymphocytes and lymphocyte subpopulations in induced sputum from asthmatic patients and from healthy subjects, and to determine the effect of inhaled an...