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非酒精性脂肪性肝病(NAFLD)包括从单纯脂肪变性到非酒精性脂肪性肝炎(NASH)等不同严重程度的肝脏病变,而NASH可发展为肝硬化并最终发展为肝细胞癌,是当前全球肝移植和肝脏相关死亡率的主要因素之一。然而,目前还没有药物被批准用于非酒精性脂肪肝的临床治疗。肝脏中脂肪酸从头合成(DNL)速率的增加是非酒精性脂肪性肝病的一个显著特征。先前的研究表明,抑制脂肪酸从头合成中的限速酶乙酰辅酶a羧化酶(AC...
Clinical Features and Treatment of 2019-nCov Pneumonia Patients in Wuhan: Report of A Couple Cases
Clinical Features Treatment 2019-nCov Pneumonia Patients Wuhan
2020/6/12
Till January 20, 2020, the 2019-new coronavirus (2019-nCoV) has caused more than one hundred cases in Wuhan (WMHC 2020). During a retrospective study of recent pneumonia patients in our department, we...
The Report of the 2017-2018 Professional Affairs Standing Committee: The Development of the Preceptor Self-Assessment Tool for Entrustable Professional Activities for New Graduates
Report Professional Affairs Standing Committee
2018/11/22
The 2017-2018 AACP Professional Affairs Committee addressed the charges of (1) developing a self-reflection/self-assessment tool for pharmacy faculty and preceptors to allow them to assess their capab...
Vital Directions for Pharmacy Education and Practice: Report of the 2017-18 Argus Commission
Directions Pharmacy Education Practice
2018/11/22
The Argus Commission examined the National Academy of Medicine’s publication “Vital Directions for Health and Health Care” and engaged with six guests from outside academic pharmacy to identify the sa...
Report of the 2017-2018 Student Affairs Standing Committee
Report Student Affairs Standing Committee
2018/11/22
The 2017-2018 American Association of Colleges of Pharmacy (AACP) Student Affairs Standing Committee addressed charges related to student wellness and resilience and identified ways where AACP can ass...
Report of the 2017-2018 Strategic Engagement Standing Committee
Report Strategic Engagement
2018/11/22
Student engagement is key to the success of schools and colleges of pharmacies in meeting their mission and programmatic needs. Student engagement in the pharmacy profession often occurs before accept...
Breaking Down Barriers to Pharmacy Graduate Education: The Report of the 2017-2018 Research and Graduate Affairs Committee
Breaking Pharmacy Graduate
2018/11/22
The 2017-2018 Research and Graduate Affairs Committee (RGAC) was given three charges aimed at helping academic pharmacy address barriers that must be overcome by both students and schools to attract, ...
A Progress Report on the State of Pharmacy Informatics Education in US Pharmacy Schools and Colleges
Progress Report the State Pharmacy
2018/11/22
Objective. To characterize informatics education opportunities in US colleges and schools of pharmacy curricula.
Methods. Informatics curricular information online was catalogued via publicly availab...
Curricular Reform in Pharmacy Education Through the Lens of the Flexner Report of 1910
Curricular Reform Pharmacy Education
2018/11/22
Abraham Flexner’s 1910 report on medical education in the United States (US) and Canada propelled medical training forward into a contemporary renaissance. The report heralded many seismic changes tha...
Stereoacuity at age 3.5 y in children born full-term is associated with prenatal and postnatal dietary factors: a report from a population–based cohort study
DHA oily fish intake visual development
2016/6/12
Observational studies suggested that breastfeeding
benefits the visual development of preterm children,
which has been attributed to the presence of docosahexaenoic
acid (DHA) in breast milk but no...
Report from a Centers for Disease Control and Prevention Workshop on Use of Adult Anthropometry for Public Health and Primary Health Care
Primary Health Care Public Health
2016/6/12
On 6 and 7 May 1999, a group of researchers from 10 countries
met in Atlanta to contemplate the simplified use of anthropometry
to assess the risk of chronic disease associated with
overweight and ...
Do we facilitate the scientific process and the development of dietary guidance when findings from single studies are publicized? An American Society for Nutritional Sciences Controversy Session Report
Dietary guidance publicity science journalism
2016/6/1
This American Society for Nutritional Sciences
Controversy Session presented at the 1997 Experimental Biology
meeting considered whether publicity of findings from single
studies facilitates or ham...
Report of a National Institutes of Health–Centers for Disease Control and Prevention workshop on the feasibility of conducting a randomized clinical trial to estimate the long-term health effects of intentional weight loss in obese persons
Obesity randomized clinical trials behavior therapy
2016/5/30
A workshop was convened in 1997 by the
National Institutes of Health and the Centers for Disease Control
and Prevention to consider the need for and feasibility of conducting
a randomized clinical ...
First Case Report of EX3del4765 Mutation in PAH Gene in Asian Population
Gene Deletion Phenylalanine Hydroxylase Phenylketonuria
2016/1/26
Introduction: Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism, which is caused by mutation in phenylalanine hydroxylase (PAH) gene. Most of the PAH mutations a...
An Unusual Complication of Ventriculoperitoneal Shunt: Urinary Bladder Stone Case Report and Literature Review
Hydrocephalus Ventriculoperitoneal Shunt Stones
2016/1/26
Introduction: Ventriculoperitoneal (V-P) shunt surgery is the most common technique used for the treatment of hydrocephalus. The migration of ventriculoperitoneal shunt to the bladder is rare. Only tw...