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A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers fou...
A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
Preventive medicine SARS-CoV-2 Viral infection
2020/6/11
An outbreak of the coronavirus disease 2019 (COVID-19)1–3, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)4 spread globally. Countermeasures are needed to treat and prevent ...
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Researchers uncover clues about how HIV virus mutates away from broadly neutralizing antibody
Researchers HIV virus mutates away broadly neutralizing antibody
2017/7/21
A new study published in Cell Host & Microbe led by researchers at Fred Hutchinson Cancer Research Center completely maps all mutations that help the HIV virus evolve away from a single broadly neutra...
Prenatal undernutrition, postnatal environments, and antibody response to vaccination in adolescence
infantile diarrhea vaccine nutrition adolescents
2016/6/14
Recently, researchers have considered the fetal
and infant origins of several adult cardiovascular and metabolic
diseases, but the implications of early events for immune function
and infectious di...
Determination and Correlation of Anticardiolipin Antibody with High Sensitivity C- reactive Proteins and its Role in Predicting Short Term Outcome in Patients with Acute Coronary Syndrome
Acute coronary syndrome Anticardiolipin antibodies
2015/7/22
Anticardiolipin antibody (aCL) is considered to be an independent risk factor while high sensitivity C reactive protein (hsCRP) is an established marker for coronary artery disease. This study was con...
Antibody's unusual abilities might inspire vaccine strategies
Antibody's unusual abilities inspire vaccine strategies
2015/5/25
The recent discovery of a novel antibody that works in an unusual way might inspire ideas for designing more effective vaccines. Among the common pathogens that might be targeted ...
Targeting treatment for colorectal cancer: the EGFR antibody story
Targeting treatment colorectal cancer
2015/4/13
Frequent overexpression of the epidermal growth factor receptor in colorectal cancer was the rationale for the development of anti-epidermal growth factor receptor antibodies. The development of the d...
Antibodies are a family of glycoproteins that bind specifically to foreign molecules (antigens). The binding between antibodies and antigens has high specificity and affinity resulting from various st...
Overcome the Impairment of NK Cells for Icon and Antibody Immunotherapy of Cancer
Natural Killer Cells Antibody Cancer Immunotherapy Icon Dietary Supplements
2013/1/30
Natural killer (NK) cells play an important role in innate immunity and in mediating antibody and Icon (an antibody-like factor VII/IgG1 Fc immunoconjugate, which, to our best knowledge, was the first...
Sensitivity and Specificity Determinations with Isoelectric Focusing Fractions of Blastomyces dermatitidis for Antibody Detection in Serum Specimens from Infected Dogs
Isoelectric Focusing ELISA Blastomycosis Lysate Antigen Antibody Detection
2013/2/19
Blastomycosis and histoplasmosis manifest as lung and systemic fungal infections in mammals caused by Histoplasma capsulatum, and Blastomyces dermatitidis. These infections exhibit cross reactivity of...
Levels of Haemophilus influenzae type B (Hib) antibody in Turkey before routine immunization
Haemophilus influenzae type b antibody serosurveillance
2010/12/21
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introductio...
Levels of Haemophilus influenzae type B (Hib) antibody in Turkey before routine immunization
Haemophilus influenzae type b antibody serosurveillance
2010/11/22
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introductio...
New antibody development brings treatment for amyloidosis a step closer
New antibody development treatment amyloidosis
2010/10/25
Scientists funded by the Medical Research Council (MRC) have devised a new approach to treat amyloidosis, according to new research published today. Systemic amyloidosis is a serious and usually fatal...
The Prevalence and Clinical Significance of Anticardiolipin Antibody in Acute Myeloblastic Leukemia
Anticardiolipin antibody Acute myeloblastic leukemia Clinical significance Iran
2015/9/21
Background: Antiphospholipid antibodies, including lupus anticoagulants and anticardiolipin (aCL) antibodies are associated with a wide variety of disorders including malignancies. The aim of this stu...