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报道2例伴少见的特征性t(11;22)(q23;q11.2)染色体异常的原发急性髓系白血病(AML)患者,探讨其临床和生物学特征。方法 对2例患者分别进行了骨髓形态学、免疫分型、染色体、荧光原位杂交(FISH)、PCR基因扩增及基因测序检查,并结合临床资料分析。结果 两例患者骨髓形态学特征分别表现为AML-M5和AML-M2,免疫分型符合AML-M5及AML-M2或M4的异常表现,与已报道的伴...
Successful Treatment of Life-Threatening Cerebral Bleeding Associated with Disseminated Intravascular Coagulation Using Recombinant Human Soluble Thrombomodulin in a Patient with Mixed Phenotype Acute Leukemia with t (9; 22) (q34; q11.2); Bcr-Abl1
Mixed Phenotype Acute Leukemia with t (9 22) (q34 q11.2) Bcr-Abl1
2013/1/29
Recently, mixed phenotype acute leukemia (MPAL) with t (9; 22) (q34; q11.2); bcr-abl1 was described as one kind of acute leukemia of ambiguous lineage in the 2008 World Health Organization Classificat...