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Postconditioning:A new link in nature’s armor against myocardial ischemia/reperfusion injury
link myocardial ischemia/reperfusion injury
2014/3/31
Area at risk myocardium after reperfusion harvested and stained with Dihydroethidium fluorescence (DHE) to visually assess generation of superoxide anions. A: IR group; B and C: area at risk myocardiu...
Activation of Src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemia
Src Phosphorylation Transient forebrain ischemia Microglia
2014/3/31
o better understand the pathophysiological role of Src protein, a non-receptor protein tyrosine kinase of 60 kDa, in the ischemic brain,
we investigated the time course and regional distribution of a...
Impairment of mitochondrial complex activity associated with ischemia and reperfusion
ischemia reperfusion mitochondrial complex
2014/3/31
It is well known that mitochondrion is the power source of cells and its function is dependent on the activities of respiratory chain complexes. In cardiac myocytes mitochondria are abundant constitut...
A NEUROPROTECTIVE ROLE OF EXTRACELLULAR SIGNAL-REGULATED KINASE IN N-ACETYL- O-METHYLDOPAMINE-TREATED HIPPOCAMPAL NEURONS AFTER EXPOSURE TO IN VITRO AND IN VIVO ISCHEMIA
ERK and CREB phosphorylation neuroprotection N-acetyl- O-methyldopamine selective neu-ronal injury oxygen-glucose deprivation transient forebrain ischemia
2014/3/31
In response to cerebral ischemia, neurons activate
survival/repair pathways in addition to death cascades. Acti-vation of cyclic AMP-response-element-binding protein
(CREB) is linked to neuroprotect...