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山西医科大学曹济民教授团队发表综述 SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development 入选ESI高被引论文和热点论文(图)
曹济民教授 山西医科大学 新型冠状病毒
2023/12/25
山西医科大学细胞生理学教育部重点实验室曹济民教授团队发表的有关新型冠状病毒的综述(Mei-Yue Wang, Rong Zhao, Li-Juan Gao, Xue-Fei Gao, De-Ping Wang, Ji-Min Cao. SARS-CoV-2: structure, biology, and structure-based therapeutics development. Fron...
2017冷泉港亚洲会议:细胞信号传导、代谢与疾病发展(Cold Spring Harbor Asia conference on Cell Signaling&Metabolism in Development&Disease)
2017 冷泉港亚洲会议 细胞信号 传导 代谢 疾病
2017/8/31
We are pleased to announce the Cold Spring Harbor Asia conference on Cell Signaling & Metabolism in Development & Disease which will be held in Suzhou, China, located approximately 60 miles west of Sh...
Gordon Research Conference on Notch Signaling in Development, Regeneration & Disease
Regeneration Disease
2016/7/29
The 2016 Gordon Research Conference on Notch Signaling in Development, Regeneration and Disease will provide a stimulating forum to discuss and disseminate new research, concepts and therapeutic oppor...
中国科学院动物研究所刘峰研究组关于Rpc9调控造血干/祖细胞命运维持的研究在Development上发表
中国科学院动物研究所 刘峰研究组 Rpc9调控造血干/祖细胞命运维持 Development
2016/5/9
脊椎动物造血干细胞在主动脉-性腺-中肾区通过内皮-造血转化过程产生,随后迁移到胎肝(人和小鼠)或尾部造血组织(斑马鱼)进行扩增和定向分化。目前,胚胎期新产生的造血干细胞的维持机制尚不完善,因此,探索这一过程中微环境信号和内源因子的系统调控作用将有助于深入了解造血干细胞发育。
Leukocytes in bovine virgin mammary gland: flow cytometry imaging during development and resolution of induced influx
bovine virgin mammary gland induced influx
2015/1/20
Distribution of leukocyte types present in virgin bovine mammary glands was analysed in dot plots obtained by flow cytometry (FACS) of samples collected from 10 non-pregnant heifers after induction of...
LymphTF Database- A Database of Transcription Factor Activity in Lymphocyte Development
lymphocyte development LymphTF Database DNA bioinformatics
2015/1/9
Study of the transcriptional regulation of lymphocyte development has advanced greatly in the past 15 years. Owing to improved techniques and intense interest in the topic, a great many interactions b...
Studies of bovine B cell development
B cells cells animals old animals spleen gene rearrangement
2014/12/11
This dissertation was to study the sites of B cell development, the mechanisms of Ig diversification, the time when diversification occurs, the B cell repertoire during development and usage of Ig lig...
{\it wingless\/} signaling in development of the {\it Drosophila\/} optic ganglia
Neuropil medulla neuropil primordium neurons optical axis innervation independent axons
2014/12/11
At the late third instar the target neuropils, the lamina and medulla neuropils, wrap around the lobula primordium, a cylinder structure called the central plug which contains a group of lobula neuron...
Overlapping and distinct functions for Gli proteins: Key mediators of hedgehog signaling in cell specification during embryonic development
Signals embryonic tissue cell differentiation the central nervous system the pituitary gland the pancreas cells
2014/12/11
Hedgehog (Hh) signaling is important for patterning and cell differentiation within many embryonic tissues. Hh is expressed in the notochord and the floor plate and acts as a morphogen in patterning o...
The role of Notch in T cell activation and development
To activate T cells incision p53 intracellular domain HES1 genes
2014/12/11
Notch is crucial for multiple stages of T cell development, including the CD4+CD8+ double positive (DP) to CD8 + single positive (SP) transition, but regulation of Notch activation is not well underst...
Multiple roles for hedgehog signaling in zebrafish pituitary development
Hedgehog signals cell type morphogenesis Hh signal spinal cord ventral cells downstream transcription factor the protein
2014/12/11
Hedgehog (Hh) signaling is required in many developmental processes including overall growth, induction of various cell types and morphogenesis. One of the earliest discoveries regarding Hh signaling ...
The impact of PCBs on thyroid hormone directed brain development in rats
Polychlorinated biphenyls (PCBS) organic pollutants biology biological systems human health polychlorinated biphenyls (PCBS)
2014/12/11
Polychlorinated biphenyls are one type of organic pollutant. Although they are no longer produced due to their resistance to degradation they have persisted in the environment and have become globally...
From Mouse Mammary Tumor Model to New Therapeutic Method ---Mammary Tumor Development in Balb/c-Trp53+/- Mice and Magnetic Nanoparticle Induced Heating for Cancer Treatment
Breast cancer Magnetic nanoparticle Mammary gland Mouse tumor model Stem cell Thermotherapy
2014/12/10
PATHWAYS CONTRIBUTING TO DEVELOPMENT OF SPONTANEOUS MAMMARY TUMORS IN BALB/c-Trp53+/- MICE Mutation and loss of p53 function are common features among human breast cancers. We use BALB/c-Trp53+/- mice...
The Role of Runx1 N-Terminal Splice Isoforms in Hematopoietic Development
Distal Isoform N-terminus Neutrophil Proximal Runx1
2014/12/10
Runx1/AML1 transcription factor expression in hematopoietic cell lineages is differentially regulated via usage of two distinct promoters. The 5' UTR and a 19 amino acid encoding sequence transcribed ...
Using new single-cell technologies, researchers create comprehensive map of human B cell development
new single-cell technologies researchers create comprehensive map human B cell development
2014/5/13
In a new paper published in the journal Cell, a team of researchers led by Dana Pe’er at Columbia University and Garry Nolan at Stanford University describes a powerful new method for mapping cellular...