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氧化三甲胺（Trimethylamine N-oxide，TMAO）是一种肠源性的菌群相关代谢产物，近年来被发现是心血管疾病和其他慢性疾病的潜在风险因子，其主要通过增加巨噬细胞中胆固醇的积累和泡沫细胞的形成、促进动脉壁的炎性反应和增加血小板高反应性等发挥致动脉粥样硬化作用。不仅如此，研究还发现TMAO与糖尿病、高血压甚至心房颤动等疾病高度相关。而缺血性卒中作为一种异质性疾病，发病机制多样。基于此，...
Salt substitution is a promising but unproven intervention for stroke management
Salt substitution promising stroke management
2018/11/20
In this issue of the Journal, Pan et al. (1) report beneficial effects on recovery after stroke with 6 mo of the postacute use of a salt substitute. The trial switched regular salt (sodium chloride) f...
Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial
stroke potassium magnesium enriched salt neurologic performance
2018/11/20
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need. Our previous intervention trial in elderly s...
Dietary glycemic index, glycemic load, and refined carbohydrates are associated with risk of stroke: a prospective cohort study in urban Chinese women
dietary carbohydrates glycemic index glycemic load stroke prospective cohort
2018/12/18
Background: Epidemiologic evidence on dietary carbohydrates and stroke risk remains controversial. Very few prospective cohort studies have been conducted in Asian populations, who usually consume a h...
ASSESSING THE POTENTIAL UTILITY OF A VIRTUAL AND MIXED/AUGMENTED REALITY SYSTEM TO ASSIST IN STROKE REHABILITATION
VIRTUAL MIXED
2015/5/27
Stroke is the number one cause of disability in the United States. This thesis summarizes current techniques and technologies for stroke rehabilitation and in addition, describes a revolutionary new c...
A non-robotic device that helps stroke survivors regain upper limb movement is expected to be commercially available in Australia within the next 12 months.
Global study shows brain damage from stroke can be minimised
brain damage electroencephalogram
2014/7/15
A new study from The University of Queensland shows monitoring the brain of stroke patients using Quantitative EEG (QEEG) studies could inform treatments and therefore, minimising brain damage of stro...
Improved treatment for stroke patients within reach
treatment stroke patients the nervous system
2009/9/28
The complex activities that occur in the human body so people can accurately reach towards objects is the subject of a new study which holds promise for improved treatment of stroke patients. Senior l...
缺血性脑卒中患者同型半胱氨酸代谢相关酶基因突变的研究 Genetic Mutations of Homocysteine Metabolism Related Enzymes in Patients with Ischemic Stroke
缺血性脑卒中 胱硫醚—β—合成酶 亚甲基四氢叶酸还原酶 基因突变 基因频率
2008/1/8
摘要
为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶(MTHFR)基因C677T和胱硫醚-β-合成酶(CBS)基因T833C位碱基突变与缺血性脑卒中的关系，对74例缺血性脑卒中患者和83例健康对照者, 采用聚合酶链反应—限制性片段长度多态性(PCR-RFLP)技术检测MTHFR基因 C677T基因型, 用扩增阻滞突变体系法(ARMS)检测CBS基因T833C突变。实验检出患者组MTHFR基因T...
Animal Models of Stroke
Animal Models Stroke
2014/3/31
Histological protection should be 70% in both transient and permanent focal ischaemia when drug is given 15–30 min post-occlusion † Must show efficacy in models of permanent MCAO †...
Although several important caveats, such as eNOS,uncoupling and the dual role of NO in brain ischemia have to be,considered,However statins, physical activity, steroid hormonesand nutrients can Le...