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Alzheimer’s risk gene undermines insulation of brain’s “wiring”（图）
阿尔茨海默氏症 风险基因 APOE4 脑细胞 隔离神经元
2023/6/21
It’s well-known that carrying one copy of the APOE4 gene variant increases one’s risk for Alzheimer’s disease threefold and two copies about tenfold, but the fundamental reasons why, and what can be d...
Native plant species may be at greater risk from climate change than non-natives（图）
Native plant species greater risk climate change non-natives
2019/10/30
As spring advances across the Midwest, a new study looking at blooming flowers suggests that climate change may cause non-native plants to outlast native plants.The study, led by scientists at Indiana...
Moderate-to-vigorous physical activity, but not sedentary time, predicts changes in cardiometabolic risk factors in 10-y-old children: the Active Smarter Kids Study
physical activity sedentary time cardiometabolic risk factors
2018/11/16
Recently, Skrede et al. (1) prospectively examined the association of objectively measured sedentary time and subcomponents of physical activity with individual and clustered cardiometabolic risk fact...
Vitamin D and dementia risk: the cause and consequence story
vitamin D dementia disentangle Indeed
2018/11/16
We read with great interest the article by Olsson et al. (1), which examined the association of vitamin D with dementia risk in a cohort of Swedish men. This study measured plasma 25-hydroxyvitamin D ...
Nutritional metabolomics and breast cancer risk in a prospective study
breast cancer diet nutrition metabolomics biomarker tocopherol alcohol androgen fat
2018/11/15
Background: The epidemiologic evidence for associations between dietary factors and breast cancer is weak and etiologic mechanisms are often unclear. Exploring the role of dietary biomarkers with meta...
Impact of breakfast skipping compared with dinner skipping on regulation of energy balance and metabolic risk
energy balance insulin sensitivity macronutrient oxidation meal skipping meal frequency
2018/11/14
Background: Meal skipping has become an increasing trend of the modern lifestyle that may lead to obesity and type 2 diabetes.
In Harm's Way:Wolves May Not Risk 'Prey Switching' say USU Ecologists
Wolves May Not Risk Prey Switching USU Ecologists
2017/4/27
Ecologists have long observed predators pursue disproportionately more of a plentiful prey species, and less of scarce prey, but change to the latter if it becomes relatively more abundant. Known as “...
Tropical lowland frogs at greater risk from climate warming than high-elevation species,study shows
Tropical lowland frogs greater risk climate warming high-elevation species
2017/4/27
A new study of Peruvian frogs living at a wide variety of elevations—from the Amazon floodplain to high Andes peaks—lends support to the idea that lowland amphibians are at higher risk from future cli...
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults
cardiometabolic risk cerebrovascular disease choline older adults magnetic resonance imaging nutrition
2018/11/14
Background: There is a potential role of choline in cardiovascular and cerebrovascular disease through its involvement in lipid and one-carbon metabolism.
A role for leukocyte integrins and extracellular matrix remodeling of adipose tissue in the risk of weight regain after weight loss
healthy overweight/obese participants human dietary intervention weight regain after weight loss adipose tissue microarray extracellular matrix and inflammation
2018/11/13
Background: Weight loss (WL) is often followed by weight regain after an energy-restricted dietary intervention (DI). When people are following a diet, the volume of an adipocyte decreases by loss of ...
Comparison of the impact of SFAs from cheese and butter on cardiometabolic risk factors: a randomized controlled trial
cardiovascular risk factors CVD dairy products men and women randomized crossover controlled trial SFA
2018/11/13
Background: Controversies persist concerning the association between intake of dietary saturated fatty acids (SFAs) and cardiovascular disease risk.
The influence of genetic susceptibility and calcium plus vitamin D supplementation on fracture risk
fracture bone mineral density genetic risk score calcium vitamin D postmenopausal women
2018/11/13
Background: Fracture is a complex trait, affected by both genetic and environmental factors. A meta-analysis of genome-wide association studies (GWASs) identified multiple bone mineral density (BMD) a...
Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study
Alzheimer disease apolipoprotein E4 cholesterol cognitive function,
2018/11/12
Background: There is little information about the associations of intakes of cholesterol and eggs, a major source of dietary cholesterol, with the risk of cognitive decline in general populations or i...
Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men
abdominal obesity cardiometabolic risk dietary weight loss flow-mediated vasodilation vascular function
2018/11/12
Background: Many trials assessing effects of dietary weight loss on vascular function have been performed without no–weight loss control groups and in individuals with obesity-related morbidities. Usu...
Dietary glycemic index, glycemic load, and refined carbohydrates are associated with risk of stroke: a prospective cohort study in urban Chinese women
dietary carbohydrates glycemic index glycemic load stroke prospective cohort
2018/12/18
Background: Epidemiologic evidence on dietary carbohydrates and stroke risk remains controversial. Very few prospective cohort studies have been conducted in Asian populations, who usually consume a h...