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High refractive index substrates for fluorescence microscopy of biological interfaces with high z contrast
Oxides Niobium Silicon Dioxide Xanthenes Lipid Bilayers Phosphatidylcholines Phosphatidylethanolamines Fluorescent Dyes Microscopy, Fluorescence Image Enhancement
2016/5/23
Total internal reflection fluorescence microscopy is widely used to confine the excitation of a complex fluorescent sample very close to the material on which it is supported. By working with high ref...
Synthesis, structural determination, and biological activity of new 7-hydroxy-3-pyrazolyl-4H-chromen- 4-ones and their o-b-D-glucosides
Chromones pyrazoles glucopyranosyl bromide glucosylation
2010/10/15
A convenient route to synthesize some new medicinally important 7-hydroxy-3-pyrazolyl chromones (3a-i) is described. The interaction of 7-hydroxy-3-formyl chromone (1) with various substituted acetoph...
Synthesis, Characterization and Biological Applications of Organotin(IV) Derivatives of 2-(2-Fluoro-4-biphenyl)propanoic Acid
Synthesis Characterization Biological 2-(2-Fluoro-4-biphenyl)propanoic Acid
2010/4/21
A series of organotin(IV) derivatives with the general formula R4 - nSnLn (where n = 1 or 2, R = Me, Et, n-Bu, Ph and L = 2-(2-fluoro-4-biphenyl)propanoate) have been synthesized and characterized by ...
Synthesis and Biological Activity of 4-(4-Hydroxybenzylidene)-2- (substituted styryl) oxazol-5-ones and Their o-glucosides
Oxazolone a -acetobromoglucose decetylation o-glucosides antimicrobial antifungal activity
2010/4/9
The 4-(4-hydroxybenzylidene)-2-methyl oxazol-5-ones 1 were treated with various aldehydes in the presence of acetic acid to form 4-(4-hydroxybenzylidene)-2-(substituted styryl) oxazol-5-ones 2a-i, whi...
Synthesis and Biological Activity of Allosteric Modulators of GABAB Receptors. Part 4. Synthesis of Potentially Fluorescent Acridines and Conformationally Restricted N-(arylpropyl)-1-arylethylamines
Fendiline analogues acridines acridones aminotetralins aminoindanes GABA
2010/4/15
A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABAB receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.
Synthesis, Spectroscopic and Biological Investigation of Cyclic Octapeptide: Cherimolacyclopeptide G
Cyclic octapeptide cherimolacyclopeptide G antibacterial activity antifungal activity anthelmintic activity cytotoxicity
2010/4/16
A natural cyclic octapeptide cherimolacyclopeptide G (8) was synthesized by coupling of tetrapeptide units Boc-Gly-Ala-Val-Pro-OMe (5) and Boc-Ile-Tyr-Ala-Pro-OMe (6) after proper deprotection at carb...
The Department of Biological Chemistry at the Grinnell College is an interdisciplinary combination of biology and chemistry requiring a distinct subset of material from both fields. The core courses o...
The Journal of Biological Inorganic Chemistry (JBIC) seeks to promote this field internationally. This journal is primarily concerned with advances in the understanding of systems involving one or mor...
The School of Biological Sciences and Applied Chemistry at Seneca College(SBSAC)
Applied Chemistry 应用化学 Biological Sciences 生物科学
2007/12/20
The School of Biological Sciences and Applied Chemistry (SBSAC) is one of several schools in the Faculty of Applied Science and Engineering Technology at Seneca College.It is located at the Seneca@Yor...
Synthesis and Biological Activities of N-Alkyl Derivatives of o-, m-, and p-Nitro (E)-4-Azachalcones and Stereoselective Photochemistry in Solution, with Theoretical Calculations
Nitro-(E)-4-azachalcones nitro-(E)-N-decyl-4-azachalconium bromide photodimerisation antimicrobial and antioxidant activities
2010/4/19
The N-alkyl derivatisation and photochemical dimerisation of 3 o-, m-, and p-nitro substituted 4-azachalcones (1-3) yielded 3 new o-, m-, and p-nitro substituted (E)-N-decyl-4-azachalconium bromides, ...
Spectroscopic Characterisation and Biological Applications of Organotin(IV) Derivatives of 3-(N-Naphthylaminocarbonyl)-2-propenoic Acid
Organotin(IV) carboxylates biological studies spectroscopic studies
2010/4/19
In an effort to develop new organotin materials for investigation and biocidal evaluation, a series of compounds with the general formula R4 - nSnLn (where R = CH3, n-C4H9, C6H5, C6H5CH2 and L = 3-(N-...
Short and Effective Synthesis of a Thiophene Analogue of (\pm)-4-Ipomeanol and Its Biological Evaluation
Sonogashira reaction 4-ipomeanol cytotoxic activity MTT assay
2010/4/19
The thiophene analogue of (\pm)-4-ipomeanol (1) was prepared in 2 steps starting from 3-iodothiophene and pent-4-yn-2-ol. The key steps were a Sonogashira reaction, followed by HgO catalysed hydratisa...
Metal Complexes of Schiff Bases: Preparation, Characterization, and Biological Activity
2-thiophenecarboxaldehyde 2-furancarboxaldehyde 2-aminothiophenol o-phenylenediamine
2010/4/19
Metal Complexes of Schiff Bases: Preparation, Characterization, and Biological Activity.
Organotin (IV) Derivatives of 1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo- 1,8-Naphthyridine-3-Carboxylic Acid (Nalidixic Acid): Synthesis, Structural Elucidation and Biological Activities
Organotin(IV) complexes 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8- naphthyridine-3-carboxylic acid (nalidixic acid) Spectroscopic characterization Biological Activity
2010/4/19
Organotin carboxylates of the general formulae R2SnL2 and R3SnL, where R = CH3, n-C4H9, C6H5, CH2C6H5 and L = 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid), h...
New Complexes of Organotin(IV) 2-(N-Maleoylamino)-2-methylpropanoate: Synthesis, Spectroscopic Characterization and Biological Activity
Organotin(IV) carboxylates spectroscopic studies biological activity
2010/4/20
Organotin(IV) complexes of 2-(N-maleoylamino)-2-methylpropanoate were prepared by treating the ligand acid with diorganotin dichloride and triorganotin chloride in 1:2 and 1:1 molar ratios, respective...