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Oxidative stress responses in Escherichia coli and Pseudomonas aeruginosa
Aerobic respiration reactive oxygen species ROS damage biological molecules cells detoxification oxidative stress transcription factors signal differential gene expression escherichia coli pseudomonas aeruginosa
2015/1/28
Aerobic respiration generates unavoidable reactive oxygen species (ROS, detrimental by-products that damage biological molecules. The accumulation of ROS beyond the cellular capacity for detoxificatio...
Structural studies of membrane-assembled PopD and PopB, the Pseudomonas aeruginosa type 3 secretion translocators
Pure sciences Biological sciences Fluorescence Membrane proteins Membranes Pore formation Type III secretion
2014/12/10
Transport of proteins across membranes is essential during many stages of pathogen infection and colonization of human cells. Many Gram-negative pathogens use a Type 3 Secretion (T3S) system to inject...
Role of a putative bacterial lipoprotein in Pseudomonas aeruginosa-mediated cytotoxicity toward airway cells
Pseudomonas aeruginosa infection Cystic Fibrosis Cytotoxicity
2015/5/22
The patients with Cystic fibrosis (CF), an inherent genetic disorder, suffer from chronic bacterial infection in the lung. In CF, modification of epithelial cells leads to alteration of the lung envir...
Antibiotic Treatment of Pseudomonas aeruginosa Biofilms Stimulates Expression of mgtE, a Virulence Modulator
Pseudomonas aeruginosa Biofilm CFBE cell AlgR mgtE co-culture virulence
2015/5/22
Pseudomonas aeruginosa is a gram negative opportunistic pathogen with the capacity to cause serious disease by forming biofilms, most notably in the lungs of cystic fibrosis (CF) patients. Biofilms ar...
Dual Functions of the Protein MgtE in Pseudomonas aeruginosa
magnesium cytotoxicity Pseudomonas cystic fibrosis biofilms virulence
2015/5/22
The Gram-negative bacterium Pseudomonas aeruginosa is an opportunistic pathogen which readily establishes itself in the lungs of people with cystic fibrosis (CF). Most CF patients have life-long P. ae...
石油发酵产蛋白酶菌株Pseudomonas aeruginosa Nu53-1减毒的研究
2007/12/29
我们在石油发酵蛋白酶产生菌的筛选工作中，获得一株能利用重油作为碳源发酵产蛋白酶的铜绿色极毛杆菌(Pseudomonas aeruginosa 6.1)[1]。此菌株经亚硝基孤及紫外线诱变处理，选出了产酶较高的变异株Nu53-1。该菌产生的蛋白酶经试验表明在皮革脱毛上具有良好的性能。