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Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how they contribute to...
Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful p...
Ateam of researchers led by Harvard and Broad Institute scientists has developed twin prime editing, a new, CRISPR-based gene-editing strategy that enables manipulation of gene-sized chunks of DNA in ...
Within the last decade, scientists have adapted CRISPR systems from microbes into gene editing technology, a precise and programmable system for modifying DNA. Now, scientists at MIT’s McGovern Instit...
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
Elizabeth Kellogg, assistant professor of molecular biology and genetics in the College of Arts and Sciences, has been named to the Pew Scholars Program to pursue research into advancing gene editing ...
In a series of experiments co-funded by the National Science Foundation, scientists at Johns Hopkins have used light as a trigger to make quick, precise cuts in the genomic material of ...
UC San Francisco researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial vi...
A next-generation gene-editing system developed by Carnegie Mellon University and Yale University scientists has cured a genetic blood disorder in living mice using a simple IV treatment. Unlike the p...
Researchers have used CRISPR—a revolutionary new genetic engineering technique—to convert cells isolated from mouse connective tissue directly into neuronal cells.In 2006, Shinya Yamanaka, a professor...
Two new studies from UC Berkeley should give scientists who use CRISPR-Cas9 for genome engineering greater confidence that they won’t inadvertently edit the wrong DNA.The gene editing technique, creat...
Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell d...
CRISPR–Cas9 represents a promising platform for genome editing, yet means for its safe and efficient delivery remain to be fully realized. A novel vehicle that simultaneously delivers the Cas9 protein...

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