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When NASA’s 990-pound Dragonfly rotorcraft reaches the Selk crater region – the mission’s target touchdown spot – on Saturn’s moon Titan in 2034, Cornell’s Léa Bonnefoy '15 will have helped to make it...
Rocks at asteroid impact site record first day of dinosaur extinction（图）
Rocks asteroid impact site record first day dinosaur extinction
2019/10/18
When the asteroid that wiped out the dinosaurs slammed into the planet, the impact set wildfires, triggered tsunamis and blasted so much sulfur into the atmosphere that it blocked the sun, which cause...
STUDY ON SITE CONDITIONS BASED ON TOPOGRAPHIC SLOPE
DEM, Topographic Slope, Vs30, Site Conditions
2018/5/15
The travel-time averaged shear-wave velocity to a depth of 30m (Vs30) below the Earth’s surface is widely used to classify sites in many building codes. Vs30 is also used to estimate site classificati...
GEOMATIC ARCHAEOLOGICAL RECONSTRUCTION AND A HYBRID VIEWER FOR THE ARCHAELOGICAL SITE OF CáPARRA (SPAIN)
Photogrammetry Reconstruction Archaeology GIS
2018/6/5
Visualization and analysis use to be the final steps in Geomatics. This paper shows the workflow followed to set up a hybrid 3D archaeological viewer. Data acquisition of the site survey was done by m...
FAILURE MECHANISM ANALYSIS CONSIDERS THE HYDROLOGICAL AND SEISMIC CONDITIONS AT CHASHAN SITE IN CENTRAL TAIWAN
Large-scale Landslide Failure Mechanism Hydrologica Seismic Scenario Simulation
2018/4/18
The investigation results of large-scale landslides in the central part of Taiwan from Central Geologic Survey identified a new, largescale landslide in the Chashan Village of Alishan Township, Chiayi...
FAILURE MECHANISM ANALYSIS CONSIDERS THE HYDROLOGICAL AND SEISMIC CONDITIONS AT CHASHAN SITE IN CENTRAL TAIWAN
Large-scale Landslide Failure Mechanism Hydrological Seismic Scenario Simulation
2018/5/8
The investigation results of large-scale landslides in the central part of Taiwan from Central Geologic Survey identified a new, largescale landslide in the Chashan Village of Alishan Township, Chiayi...
NASA recorded thousands of hours of audio from the Apollo lunar missions, yet most of us have only been able to hear the highlights.The agency recorded all communications between the astronauts, missi...
NSF awards $5.6 million to establish new arctic Long-Term Ecological Research site
NSF $5.6 million new arctic Long-Term Ecological Research site
2017/3/30
The National Science Foundation (NSF) has made a $5.6 million, five-year grant to establish a Long-Term Ecological Research (LTER) site along the northern Alaskan coast that will focus on the interact...
Exceptionally preserved Jurassic sea life found in new fossil site
Jurassic sea life new fossil site
2017/2/16
A trove of exceptionally preserved Jurassic marine fossils discovered in Canada, rare for recording soft-bodied species that normally don’t fossilize, is expanding scientists’ view of the rich marine ...
Quantum delocalization of protons in the hydrogen-bond network of an enzyme active site
ab initio path integral molecular dynamics enzyme hydrogen bonding nuclear quantum effects proton delocalization
2016/5/25
Enzymes use protein architectures to create highly specialized structural motifs that can greatly enhance the rates of complex chemical transformations. Here, we use experiments, combined with ab init...
Extreme Electric Fields Power Catalysis in the Active Site of Ketosteroid Isomerase
Electric Power Catalysis Active Site Ketosteroid Isomerase
2016/5/25
Enzymes use protein architecture to impose specific electrostatic fields onto their bound substrates, but the magnitude and catalytic effect of these electric fields have proven difficult to quantify ...
Quantitative Dissection of Hydrogen Bond-Mediated Proton Transfer in the Ketosteroid Isomerase Active Site
active site environment computational modeling enzyme catalysis protein electrostatics protein semisynthesis
2016/5/25
Hydrogen bond networks are key elements of protein structure and function but have been challenging to study within the complex protein environment. We have carried out in-depth interrogations of the ...
Site-Specific Measurement of Water Dynamics in the Substrate Pocket of Ketosteroid Isomerase Using Time-Resolved Vibrational Spectroscopy
IL-33 ST2 MWCNTs pulmonary fibrosis nanotoxicology
2016/5/25
Little is known about the reorganization capacity of water molecules at the active sites of enzymes and how this couples to the catalytic reaction. Here, we study the dynamics of water molecules at th...
Quantitative,Directional Measurement of Electric Field Heterogeneity Within an Enzyme Active Site
Quantitative Directional Measurement Electric Field Heterogeneity Enzyme Active Site
2016/5/25
Extensive structural studies of enzymes have revealed that biological catalysis occurs within sequestered active site crevices, where reacting substrates are surrounded by an anisotropic and chemicall...
Electrostatic Fields Near the Active Site of Human Aldose Reductase:2.New Inhibitors and Complications Caused by Hydrogen Bonds
Humans Nitriles Aldehyde Reductase Spectrophotometry, Infrared Spectroscopy, Fourier Transform Infrared Binding Sites Catalytic Domain Protein Binding Kinetics Hydrogen Bonding
2016/5/25
Vibrational Stark effect spectroscopy was used to measure electrostatic fields in the hydrophobic region of the active site of human aldose reductase (hALR2). A new nitrile-containing inhibitor was de...