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Higgs Discovery and the Look Elsewhere Effect
Higgs particle discovery condition Bayesianism 5 sigma limit collider physics
2016/6/12
The discovery of the Higgs particle required a signal of five sigma significance. The rigid application of that condition is a convention that disregards more specific aspects of the given experiment....
Decision and discovery in defining 'disease'
Biology Diagnosis Disease Medicine Metaphysics
2014/11/17
The debate over how to analyze the concept of disease has often centered on the question of whether to include a reference to values, in particular the ‘disvalue’of diseases, or whether to avoid such ...
Scientific Reasoning Is Material Inference: Combining Confirmation, Discovery, and Explanation
inference concepts confirmation induction
2009/9/11
Whereas an inference (deductive as well as inductive) is usually viewed as being valid in virtue of its argument form, the present paper argues that scientific reasoning is material inference, i.e., j...
How Values in Scientific Discovery and Pursuit Alter Theory Appraisal
scientific discovery pursuit non-epistemic values hormesis endocrine disruption
2009/6/24
Philosophers of science readily acknowledge that non-epistemic values influence the discovery and pursuit of scientific theories, but many tend to regard these influences as epistemically uninterestin...
Multi-level complexities in technological development: Competing strategies for drug discovery
applied science pharmaceuticals development methodology technology
2009/4/29
Drug development regularly has to deal with complex circumstances on two levels: the local level of pharmacological intervention on specific target proteins, and the systems level of the effects of ph...
The purpose of this paper is to discuss and clarify the explanations commonly cited for the aerodynamic lift generated by a wing, and to then analyse, as a case study of engineering discovery, the aer...
Model, Theory, and Evidence in the Discovery of the DNA Structure
DNA structure model-building phenomenologically-driven view
2008/4/15
In this paper I discuss the discovery of the DNA structure by Francis Crick and James Watson, which has provoked a large historical literature but has yet not found entry into philosophical debates. I...
Discerning a Signal from Noise: The Discovery of Weak Neutral Currents reconsidered
high energy physics discovery of Weak Neutral Currents
2008/4/11
In this paper I try to shed some light on how one discerns a physical ‘signal’ from ‘noise’ in experimental science. To this end I revisit the discovery of Weak Neutral Currents (WNC), on which some o...
Jerome A. Berson: Chemical Discovery and the Logicians’ Program. A Problematic Pairing, Wiley-VCH, Weinheim, 2003, xiii + 194 pp. [ISBN 3-527-30797-4]
Jerome A. Berson Chemical Discovery the Logicians’ Program
2008/4/3
The question posed in this book is of obvious interest to the readership of Hyle: Do philosophers of science provide useful roadmaps to professional chemists? While the author answers in the negative,...